ArticleScientific reports2016
Transcriptome assembly and expression profiling of molecular responses to cadmium toxicity in hepatopancreas of the freshwater crab Sinopotamon henanense.
Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 97 citations in OpenAlex.
- Physiological and Proteomic Insights into Melatonin-Mediated Regulation of Copper Toxicity in the CrayfishInternational journal of molecular sciences · 2026Article
- Cadmium-induced DAG-PKC/IP3-Ca2+ double signaling pathway and cell injury in gill of freshwater crabs Sinopotamon henanense.PloS one · 2026Article
- Study on the Mechanism and Potential of Corbicula fluminea (Asian Clam) in Removing Copper and Cadmium from Aquaculture Ponds.Marine biotechnology (New York, N.Y.) · 2024Article
- Saccharomyces cerevisiae additions normalized hemocyte differential genes expression and regulated crayfish (Procambarus clarkii) oxidative damage under cadmium stress.Scientific reports · 2023Article
- Preliminary study on toxicological mechanism of golden cuttlefish (Sepia esculenta) larvae exposed to cd.BMC genomics · 2023Article
- Mercury Induced Tissue Damage, Redox Metabolism, Ion Transport, Apoptosis, and Intestinal Microbiota Change in Red Swamp Crayfish (Antioxidants (Basel, Switzerland) · 2022Article
- Transcriptomic and Histological Analysis of the Greentail Prawn (Metapenaeus bennettae) Following Light Crude Oil Exposure.Environmental toxicology and chemistry · 2022Article
- From Mangrove to Fork: Metal Presence in the Guayas Estuary (Ecuador) and Commercial Mangrove Crabs.Foods (Basel, Switzerland) · 2021Article
- Comparative transcriptome analysis of the gills and hepatopancreas from Macrobrachium rosenbergii exposed to the heavy metal Cadmium (CdScientific reports · 2021Article
- Identification of Sex-Related Genes from the Three-Spot Swimming CrabAnimals : an open access journal from MDPI · 2021Article
- Toxic effects of metal copper stress on immunity, metabolism and pathologic changes in Chinese mitten crab (Eriocheir japonica sinensis).Ecotoxicology (London, England) · 2021Article
- Transcriptome Analysis of the Hepatopancreas in the Litopenaeus vannamei Responding to the Lead Stress.Biological trace element research · 2021Article
- Hyperaccumulation of cadmium by scallop Chlamys farreri revealed by comparative transcriptome analysis.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2020Article
- Effects of lead and cadmium on the immune system and cancer progression.Journal of environmental health science & engineering · 2020Review
- Metal stress-related gene expression patterns in two marine invertebrates, Hediste diversicolor (Annelida, Polychaeta) and Littorina littorea (Mollusca, Gastropoda), at a former mining site.Comparative biochemistry and physiology. Toxicology & pharmacology : CBP · 2019Article
- Comparative transcriptome analysis in the hepatopancreas of Helice tientsinensis exposed to the toxic metal cadmium.Genes & genomics · 2019Article
- Identification and profiling of microRNAs responsive to cadmium toxicity in hepatopancreas of the freshwater crabHereditas · 2019Article
- Transcriptome analysis reveals the molecular response to cadmium toxicity in P. pseudoannulata.Environmental science and pollution research international · 2018Article
- Transcriptome sequencing and molecular markers discovery in the gonads of Portunus sanguinolentus.Scientific data · 2018Article
- Transcriptome assembly and expression profiling of the molecular responses to cadmium toxicity in cerebral ganglia of wolf spider Pardosa pseudoannulata (Araneae: Lycosidae).Ecotoxicology (London, England) · 2018Article
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cadmium (Cd) pollution is a serious global problem, which causes irreversible toxic effects on animals. Freshwater crab, Sinopotamon henanense, is a useful environmental indicator since it is widely distributed in benthic habitats whereby it tends to accumulate Cd and other toxicants. However, its molecular responses to Cd toxicity remain unclear. In this study, we performed transcriptome sequencing and gene expression analyses of its hepatopancreas with and without Cd treatments. A total of 7.78 G clean reads were obtained from the pooled samples, and 68,648 unigenes with an average size of 622 bp were assembled, in which 5,436 were metabolism-associated and 2,728 were stimulus response-associated that include 380 immunity-related unigenes. Expression profile analysis demonstrated that most genes involved in macromolecular metabolism, oxidative phosphorylation, detoxification and anti-oxidant defense were up-regulated by Cd exposure, whereas immunity-related genes were down-regulated, except the genes involved in phagocytosis were up-regulated. The current data indicate that Cd exposure alters gene expressions in a concentration-dependent manner. Therefore, our results provide the first comprehensive S.henanense transcriptome dataset, which is useful for biological and ecotoxicological studies on this crab and its related species at molecular level, and some key Cd-responsive genes may provide candidate biomarkers for monitoring aquatic pollution by heavy metals.
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