ArticlePsychological medicine2016
Disruptive mood dysregulation disorder at the age of 6 years and clinical and functional outcomes 3 years later.
Article in Psychological medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it, 45 citations in OpenAlex.
- Diagnostic instruments for the assessment of disruptive mood dysregulation disorder: a systematic review of the literature.European child & adolescent psychiatry · 2023Pooled it
- Characterizing Early Childhood Disruptive Mood Dysregulation Disorder.JAACAP open · 2026Article
- Comparison of Global and Daily Ratings of Associations between Anxiety and Depressive Behaviors and Impairment in Preschool-Aged Children.Child psychiatry and human development · 2026Article
- The hidden burden: self-reported irritability in adolescent girls signals higher psychiatric risk.BMC public health · 2025Article
- Cord serum cytokines at birth and children's trajectories of mood dysregulation symptoms from 3 to 8 years: The EDEN birth cohort.Brain, behavior, & immunity - health · 2024Article
- Peer functioning difficulties may exacerbate symptoms of attention-deficit/hyperactivity disorder and irritability over time: a temporal network analysis.Journal of child psychology and psychiatry, and allied disciplines · 2024Article
- Parent and Teacher Ratings of Tonic and Phasic Irritability in a Clinical Sample.Research on child and adolescent psychopathology · 2024Article
- An Expanded Conceptual Framework for Understanding Irritability in Childhood: The Role of Cognitive Control Processes.Clinical child and family psychology review · 2024Review
- Irritability in Youths: A Critical Integrative Review.The American journal of psychiatry · 2024Review
- The DADYS-Screen: Development and Evaluation of a Screening Tool for Affective Dysregulation in Children.Assessment · 2023Article
- Context-dependent amygdala-prefrontal connectivity during the dot-probe task varies by irritability and attention bias to angry faces.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2022Article
- Psychometric Validation of the Greek Version of the Scale "Temper Loss" of the Questionnaire "Multidimensional Assessment Profile of Disruptive Behavior (MAP-DB)".Children (Basel, Switzerland) · 2022Article
- Trajectory of emotion dysregulation in positive and negative affect across childhood predicts adolescent emotion dysregulation and overall functioning.Development and psychopathology · 2021Article
- Preventing Irritability and Temper Outbursts in Youth by Building Resilience.Child and adolescent psychiatric clinics of North America · 2021Review
- Attention shifting in the context of emotional faces: Disentangling neural mechanisms of irritability from anxiety.Depression and anxiety · 2020Article
- Excitability and irritability in preschoolers predicts later psychopathology: The importance of positive and negative emotion dysregulation.Development and psychopathology · 2019Article
- A Review on the General Stability of Mood Disorder Diagnoses Along the Lifetime.Current psychiatry reports · 2018Review
- Identifying Clinically Significant Irritability in Early Childhood.Journal of the American Academy of Child and Adolescent Psychiatry · 2018Article
- Predictors of Later Psychopathology in Young Children with Disruptive Mood Dysregulation Disorder.Journal of child and adolescent psychopharmacology · 2017Article
- Perinatal and postnatal risk factors for disruptive mood dysregulation disorder at age 11: 2004 Pelotas Birth Cohort Study.Journal of affective disorders · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 4 institutions in 1 country.
Funding
Abstract
backgroundLittle is known about the predictive validity of disruptive mood dysregulation disorder (DMDD). This longitudinal, community-based study examined associations of DMDD at the age of 6 years with psychiatric disorders, functional impairment, peer functioning and service use at the age of 9 years.
methodA total of 473 children were assessed at the ages of 6 and 9 years. Child psychopathology and functional impairment were assessed at the age of 6 years with the Preschool Age Psychiatric Assessment with parents and at the age of 9 years with the Kiddie-Schedule of Affective Disorders and Schizophrenia (K-SADS) with parents and children. At the age of 9 years, mothers, fathers and youth completed the Child Depression Inventory (CDI) and the Screen for Child Anxiety Related Disorders, and teachers and K-SADS interviewers completed measures of peer functioning. Significant demographic covariates were included in all models.
resultsDMDD at the age of 6 years predicted a current diagnosis of DMDD at the age of 9 years. DMDD at the age of 6 years also predicted current and lifetime depressive disorder and attention-deficit/hyperactivity disorder (ADHD) at the age of 9 years, after controlling for all age 6 years psychiatric disorders. In addition, DMDD predicted depressive, ADHD and disruptive behavior disorder symptoms on the K-SADS, and maternal and paternal reports of depressive symptoms on the CDI, after controlling for the corresponding symptom scale at the age of 6 years. Last, DMDD at the age of 6 years predicted greater functional impairment, peer problems and educational support service use at the age of 9 years, after controlling for all psychiatric disorders at the age of 6 years.
conclusionsChildren with DMDD are at high risk for impaired functioning across childhood, and this risk is not accounted for by co-morbid conditions.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.