ReviewCardiovascular research2016
Presence and stability of rotors in atrial fibrillation: evidence and therapeutic implications.
Review in Cardiovascular research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed, 69 citations in OpenAlex.
- High-Density Spectral Analysis for Bi-Atrial Arrhythmogenic Substrate During Non-Paroxysmal Atrial Fibrillation.Journal of arrhythmia · 2026Article
- Machine learning for enhancing the ablation outcomes using recurrence quantification analysis in human persistent atrial fibrillation.Frontiers in physiology · 2026Article
- Complexity and recurrence of body surface electrocardiograms correlate with estimated reentrant atrial activity using electrocardiographic imaging in atrial fibrillation patients.BMC cardiovascular disorders · 2025Article
- Distributions and number of drivers on real-time phase mapping associated with successful atrial fibrillation termination during catheter ablation for non-paroxysmal atrial fibrillation.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2024Article
- Electrographic flow mapping of persistent atrial fibrillation: intra- and inter-procedure reproducibility in the absence of 'ground truth'.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2023Article
- Atrial Fibrillation and Chronic Coronary Ischemia: A Challenging Vicious Circle.Life (Basel, Switzerland) · 2023Review
- Electrographic flow mapping for atrial fibrillation: theoretical basis and preliminary observations.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2023Review
- Organization of atrial fibrillation using a pure sodium channel blocker: Implications of rotor ablation therapy.Journal of arrhythmia · 2023Article
- Electrocardiographic imaging in the atria.Medical & biological engineering & computing · 2023Review
- AF driver detection in pulmonary vein area by electropcardiographic imaging: Relation with a favorable outcome of pulmonary vein isolation.Frontiers in physiology · 2023Article
- High-density mapping of the average complex interval helps localizing atrial fibrillation drivers and predicts catheter ablation outcomes.Frontiers in cardiovascular medicine · 2023Article
- Panoramic Endocardial Optical Mapping Demonstrates Serial Rotors Acceleration and Increasing Complexity of Activity During Onset of Cholinergic Atrial Fibrillation.Journal of the American Heart Association · 2021Article
- First-in-human demonstration of 18-month spatiotemporal stability of active atrial fibrillation source detected by electrographic flow mapping in persistent atrial fibrillation.HeartRhythm case reports · 2021Article
- Article
- The Electrophysiology of Atrial Fibrillation: From Basic Mechanisms to Catheter Ablation.Cardiology research and practice · 2021Article
- Electrocardiographic Imaging for Atrial Fibrillation: A Perspective From Computer Models and Animal Experiments to Clinical Value.Frontiers in physiology · 2021Review
- Atrial proarrhythmic effect of lead as one of the PM10 metal components of air pollution. An in-silico study.PloS one · 2021Article
- Non-invasive Estimation of Atrial Fibrillation Driver Position With Convolutional Neural Networks and Body Surface Potentials.Frontiers in physiology · 2021Article
- Rotor Localization and Phase Mapping of Cardiac Excitation Waves Using Deep Neural Networks.Frontiers in physiology · 2021Article
- Automatic quality electrogram assessment improves phase-based reentrant activity identification in atrial fibrillation.Computers in biology and medicine · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 4 institutions in 2 countries.
Funding
Abstract
Rotor-guided ablation has opened new perspectives into the therapy of atrial fibrillation (AF). Analysis of the spatio-temporal cardiac excitation patterns in the frequency and phase domains has demonstrated the importance of rotors in research models of AF, however, the dynamics and role of rotors in human AF are still controversial. In this review, the current knowledge gained through research models and patient data that support the notion that rotors are key players in AF maintenance is summarized. We report and discuss discrepancies regarding rotor prevalence and stability in various studies, which can be attributed in part to methodological differences among mapping systems. Future research for validation and improvement of current clinical electrophysiology mapping technologies will be crucial for developing mechanistic-based selection and application of the best therapeutic strategy for individual AF patient, being it, pharmaceutical, ablative, or other approach.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.