Evidence map›Paper›PMID 26785845›Full record

ArticleBiomechanics and modeling in mechanobiology2016

3D finite element model of the chinchilla ear for characterizing middle ear functions.

Xuelin Wang, Rong Z Gan

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomechanics and modeling in mechanobiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
3.1field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Article
  3. Developing a Virtual Model of the Rhesus Macaque Inner Ear.Bioengineering (Basel, Switzerland) · 2024
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Panel 1: Biotechnology, biomedical engineering and new models of otitis media.International journal of pediatric otorhinolaryngology · 2020
    Review
  13. The chinchilla animal model for hearing science and noise-induced hearing loss.The Journal of the Acoustical Society of America · 2019
    Review
  14. A lumped-element model of the chinchilla middle ear.The Journal of the Acoustical Society of America · 2019
    Article
  15. Surface Motion of Tympanic Membrane in a Chinchilla Model of Acute Otitis Media.Journal of the Association for Research in Otolaryngology : JARO · 2018
    Article
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Xuelin WangSchool of Aerospace and Mechanical Engineering and Biomedical Engineering Center, University of Oklahoma, 865 Asp Avenue, Room 200, Norman, OK, 73019, USA.
Rong Z GanSchool of Aerospace and Mechanical Engineering and Biomedical Engineering Center, University of Oklahoma, 865 Asp Avenue, Room 200, Norman, OK, 73019, USA. rgan@ou.edu.
Huazhong University of Science and Technology · CNUniversity of Oklahoma · US

Funding

Biomechanical Measurement and Modeling of Normal and Diseased Middle EarsR01DC011585 · NIDCD · UNIVERSITY OF OKLAHOMA · PI GAN, RONG Z · 2011 to 2015
$1.7M
NIDCD NIH HHS R01 DC011585
6 · The paper itself

Abstract

Chinchilla is a commonly used animal model for research of sound transmission through the ear. Experimental measurements of the middle ear transfer function in chinchillas have shown that the middle ear cavity greatly affects the tympanic membrane (TM) and stapes footplate (FP) displacements. However, there is no finite element (FE) model of the chinchilla ear available in the literature to characterize the middle ear functions with the anatomical features of the chinchilla ear. This paper reports a recently completed 3D FE model of the chinchilla ear based on X-ray micro-computed tomography images of a chinchilla bulla. The model consisted of the ear canal, TM, middle ear ossicles and suspensory ligaments, and the middle ear cavity. Two boundary conditions of the middle ear cavity wall were simulated in the model as the rigid structure and the partially flexible surface, and the acoustic-mechanical coupled analysis was conducted with these two conditions to characterize the middle ear function. The model results were compared with experimental measurements reported in the literature including the TM and FP displacements and the middle ear input admittance in chinchilla ear. An application of this model was presented to identify the acoustic role of the middle ear septa-a unique feature of chinchilla middle ear cavity. This study provides the first 3D FE model of the chinchilla ear for characterizing the middle ear functions through the acoustic-mechanical coupled FE analysis.

Indexed as

Finite Element AnalysisImaging, Three-DimensionalModels, BiologicalAcousticsAnimalsChinchillaEar, MiddlePressureTympanic MembraneX-Ray MicrotomographyBiomechanics of hearingFinite element modelFluid–structure interactionMiddle ear

Identifiers

PMID26785845
PMCPMC4955651
OpenAlexW2295285976

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.