ArticleBMC pregnancy and childbirth2016
Vitamin D deficiency and supplementation in pregnancy in a multiethnic population-based cohort.
Article in BMC pregnancy and childbirth, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 3 of them syntheses that pooled it.
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Who cites it
25 citing papers in PubMed, 3 syntheses or guidelines pooled it, 90 citations in OpenAlex.
- Circulating vitamin D and the risk of gestational diabetes: a systematic review and dose-response meta-analysis.Endocrine · 2020Pooled it
- Associations of Maternal Vitamin D Deficiency with Pregnancy and Neonatal Complications in Developing Countries: A Systematic Review.Nutrients · 2018Pooled it
- Pooled it
- Preconception vitamin D status and subsequent risk of preeclampsia: A secondary cohort analysis from the EAGeR trial.Pregnancy hypertension · 2026Trial
- Impact of trimester-specific nutrition counseling on maternal vitamin D status, and perinatal outcomes in India: a quasi-experimental cohort study.BMC public health · 2026Article
- Necrotizing Enterocolitis: A Comprehensive Review on Toll-like Receptor 4-Mediated Pathophysiology, Clinical, and Therapeutic Insights.Biomedicines · 2025Review
- The potential impact of the extended vitamin D fortification policy during pregnancy varies by continent of origin - a population-representative Swedish cohort.European journal of nutrition · 2025Article
- Review
- Maternal vitamin D levels during pregnancy and offspring schizophrenia.Schizophrenia research · 2024Article
- Vitamin D levels of pregnant immigrant women and developmental disorders of language, learning and coordination in offspring.PloS one · 2024Article
- Maternal plasma vitamin D levels across pregnancy are not associated with neonatal birthweight: findings from an Australian cohort study of low-risk pregnant women.BMC pregnancy and childbirth · 2023Article
- Vitamin D intake and determinants of vitamin D status during pregnancy in The Norwegian Mother, Father and Child Cohort Study.Frontiers in nutrition · 2023Article
- Prevalence of postpartum anaemia and iron deficiency by serum ferritin, soluble transferrin receptor and total body iron, and associations with ethnicity and clinical factors: a Norwegian population-based cohort study.Journal of nutritional science · 2022Article
- Knowledge, attitude, performance, and determinant factors of Vitamin D deficiency prevention behaviours among Iranian pregnant women.Archives of public health = Archives belges de sante publique · 2021Article
- Maternal Vitamin D Levels and the Risk of Offspring Attention-Deficit/Hyperactivity Disorder.Journal of the American Academy of Child and Adolescent Psychiatry · 2021Article
- Association between variants in vitamin D-binding protein gene and vitamin D deficiency among pregnant women in china.Journal of clinical laboratory analysis · 2020Article
- Vitamin D deficiency in western dwelling South Asian populations: an unrecognised epidemic.The Proceedings of the Nutrition Society · 2020Review
- Maternal vitamin D status during pregnancy and offspring risk of childhood/adolescent depression: Results from the Avon Longitudinal Study of Parents and Children (ALSPAC).Journal of affective disorders · 2020Article
- Daily versus stat vitamin D supplementation during pregnancy; A prospective cohort study.PloS one · 2020Article
- Associations of maternal vitamin D, PTH and calcium with hypertensive disorders of pregnancy and associated adverse perinatal outcomes: Findings from the Born in Bradford cohort study.Scientific reports · 2019Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTo investigate ethnic differences in vitamin D levels during pregnancy, assess risk factors for vitamin D deficiency and explore the effect of vitamin D supplementation in women with deficiency in early pregnancy.
methodsThis is a population-based, multiethnic cohort study of pregnant women attending Child Health Clinics for antenatal care in Oslo, Norway. Serum-25-hydroxyvitamin D [25(OH)D] was measured in 748 pregnant women (59% ethnic minorities) at gestational weeks (GW) 15 (SD:3.6) and 28 (1.4). Women with 25(OH)D <37 nmol/L at GW 15 were for ethical reasons recommended vitamin D3 supplementation. Main outcome measure was 25(OH)D, and linear regression models were performed.
resultsSevere deficiency (25(OH)D <25 nmol/L) was found at GW 15 in 45% of women from South Asia, 40% from the Middle East and 26% from Sub-Saharan Africa, compared to 2.5% in women from East Asia and 1.3% of women from Western Europe. Women from South Asia, the Middle East and Sub-Saharan Africa had mean values that were -28 (95 % CI:-33, -23), -24 (-29, -18) and -20 (-27, -13) nmol/L lower than in Western women, respectively. Ethnicity, education, season and intake of vitamin D were independently associated with 25(OH)D. At GW 28, the mean 25(OH)D had increased from 23 (SD:7.8) to 47 (27) nmol/L (p < 0.01) in women who were recommended vitamin D supplementation, with small or no change in women with sufficient vitamin D levels at baseline.
conclusionsVitamin D deficiency was prevalent among South Asian, Middle Eastern and African women. The serum levels of 25(OH)D increased significantly from GW 15 to 28 in vitamin D deficient women who received a recommendation for supplementation. This recommendation of vitamin D supplementation increased vitamin D levels in deficient women.
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