ArticleScientific reports2016
Skeletal muscle mass adjusted by height correlated better with muscular functions than that adjusted by body weight in defining sarcopenia.
Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 66 papers, 4 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
66 citing papers in PubMed, 4 syntheses or guidelines pooled it, 111 citations in OpenAlex.
- Prevalence of sarcopenia in older Chinese adults: a systematic review and meta-analysis.BMJ open · 2021Pooled it
- The Prevalence of Sarcopenia in Chinese Older Adults: Meta-Analysis and Meta-Regression.Nutrients · 2021Pooled it
- Pooled it
- Differences in handgrip strength protocols to identify sarcopenia and frailty - a systematic review.BMC geriatrics · 2017Pooled it
- Trial
- Effects of Multicomponent Otago Exercise Program with Added Resistance Training on Sarcopenia in Pre-Frailty Older Adults in Nursing Homes: A Randomized Controlled Trial.Clinical interventions in aging · 2025Trial
- Association of muscle mass and strength with blood-based epigenetic aging among middle-aged and older adults in the United States.GeroScience · 2026Article
- Article
- Gingival bleeding and lower number of natural teeth are predictive factors of low muscle strength in obese adults: a cross-sectional study.Frontiers in oral health · 2026Article
- Relationship Between Weight, Muscle Mass, Cardiorespiratory Endurance, and Likelihood of Dynapenia in Older Adults.Journal of aging research · 2026Article
- Associations Between the Severity of Sarcopenia and Health-Related Quality of Life in Older Adults.Journal of clinical medicine · 2025Article
- Predicting Sarcopenia in Peritoneal Dialysis Patients: A Multimodal Ultrasound-Based Logistic Regression Analysis and Nomogram Model.Diagnostics (Basel, Switzerland) · 2025Article
- Research progress on evaluation methods for skeletal muscle mass assessment in sarcopenia (Review).Oncology letters · 2025Review
- Review
- Plasma Extracellular Vesicles Biomarkers Linked to Lower Muscle Mass, Function and Physical Performance in Sarcopenia.Journal of cachexia, sarcopenia and muscle · 2025Article
- Review
- Positive Changes in Functional Capacity, Muscle Strength and Body Composition after Short Time of Resistance Training Periodization in Older Women: A Quasi-experimental Study.International journal of exercise science · 2025Article
- Article
- Relationship between different muscle mass indices and physical performance measures in Turkish older adults.BMC geriatrics · 2024Article
- Novel metabolic and lipidomic biomarkers of sarcopenia.Journal of cachexia, sarcopenia and muscle · 2024Article
6 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Sarcopenia, characterized by low muscle mass and function, results in frailty, comorbidities and mortality. However, its prevalence varies according to the different criteria used in its diagnosis. This cross-sectional study investigated the difference in the number of sarcopenia cases recorded by two different measurement methods of low muscle mass to determine which measurement was better. We recruited 878 (54.2% female) individuals aged over 65 years and obtained their body composition and functional parameters. Low muscle mass was defined as two standard deviations below either the mean height-adjusted (hSMI) or weight-adjusted (wSMI) muscle mass of a young reference group. The prevalence of sarcopenia was 6.7% vs. 0.4% (male/female) by hSMI, and 4.0% vs. 10.7% (male/female) by wSMI. The κ coefficients for these two criteria were 0.39 vs. 0.03 (male/female), and 0.17 in all subjects. Serum myostatin levels correlated positively with gait speed (r = 0.142, p = 0.007) after adjustment for gender. hSMI correlated with grip strength, cardiopulmonary endurance, leg endurance, gait speed, and flexibility. wSMI correlated with grip strength, leg endurance, gait speed, and flexibility. Since hSMI correlated more closely with grip strength and more muscular functions, we recommend hSMI in the diagnosis of low muscle mass.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.