ArticleThe International journal of neuroscience2017
Aerobic exercise improves measures of vascular health in diabetic peripheral neuropathy.
Article in The International journal of neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04807452 (Effects of Strength And Balance Training on Diabetic Peripheral Neuropathy), which is not on this map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effects of Strength And Balance Training on Diabetic Peripheral Neuropathy
Who cites it
18 citing papers in PubMed, 27 citations in OpenAlex.
- Effects of Computer-based Balance Exercises on Balance, Pain, Clinical Presentation and Nerve Function in Patients With Diabetic Peripheral Neuropathy: A Randomized Controlled Study.Journal of musculoskeletal & neuronal interactions · 2024Trial
- Amyloid-β: A potential mediator of aging-related vascular pathologies.Vascular pharmacology · 2023Review
- The Application of Exercise Training for Diabetic Peripheral Neuropathy.Journal of clinical medicine · 2021Review
- Lower extremity MRI following 10-week supervised exercise intervention in patients with diabetic peripheral neuropathy.BMJ open diabetes research & care · 2021Article
- The efficacy of physiotherapy interventions in mitigating the symptoms and complications of diabetic peripheral neuropathy: A systematic review.Journal of diabetes and metabolic disorders · 2020Review
- Cardiovascular disease risk is associated with middle cerebral artery blood flow velocity in older adults.Cardiopulmonary physical therapy journal · 2020Article
- Aerobic exercise can modulate the underlying mechanisms involved in the development of diabetic complications.Journal of cellular physiology · 2019Review
- Exercise intensity and middle cerebral artery dynamics in humans.Respiratory physiology & neurobiology · 2019Article
- Blunted cerebrovascular response is associated with elevated beta-amyloid.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2019Article
- Vascular Health is Associated with Amyloid-β in Cognitively Normal Older Adults.Journal of Alzheimer's disease : JAD · 2019Article
- Effect of healthy aging and sex on middle cerebral artery blood velocity dynamics during moderate-intensity exercise.American journal of physiology. Heart and circulatory physiology · 2018Article
- Neuroprotective strategies for retinal disease.Progress in retinal and eye research · 2018Review
- TrkB signalling pathway mediates the protective effects of exercise in the diabetic rat retina.The European journal of neuroscience · 2018Article
- The effects of exercise on vascular endothelial function in type 2 diabetes: a systematic review and meta-analysis.Diabetology & metabolic syndrome · 2018Review
- Declining Skeletal Muscle Function in Diabetic Peripheral Neuropathy.Clinical therapeutics · 2017Review
- Dynamics of middle cerebral artery blood flow velocity during moderate-intensity exercise.Journal of applied physiology (Bethesda, Md. : 1985) · 2017Article
- Preliminary Evidence for the Impact of Combat Experiences on Gray Matter Volume of the Posterior Insula.Frontiers in psychology · 2017Article
- Pilot Investigation of PTSD, Autonomic Reactivity, and Cardiovascular Health in Physically Healthy Combat Veterans.PloS one · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
aimsAerobic exercise improves vascular endothelial function in people with Type 2 diabetes mellitus (T2DM). There is minimal information available regarding vascular health in people with T2DM and diabetic peripheral neuropathy (DPN). Thus, the primary aim of this secondary analysis was to determine whether a 16-week aerobic exercise intervention could improve vascular health in people with T2DM and DPN. A secondary aim was to explore the relationship between changes in flow-mediated dilation (FMD) and the number of years since diagnosis of DPN.
methodsWe examined whether a 16-week aerobic exercise intervention would improve vascular health in people with T2DM and DPN. We used Doppler ultrasound to assess brachial artery diameter and peak shear at baseline and post-exercise. Paired t-tests were used to determine whether the outcome measures improved from baseline to post-intervention. Pearson correlation assessed the relationship between DPN (years) and the percent change score (pre- to post-intervention) for FMD.
resultsSeventeen individuals were included in the data analysis. After the intervention, peak diameter increased (3.9 (0.5) to 4.0 (0.5) mm; p = 0.07). Time to peak shear occurred at 60.5 (24.6) seconds when compared to baseline at 68.2 (22.7) seconds; p = 0.17. We found that a longer duration (in years) of DPN demonstrated a fair, negative relationship (r = -0.41, p = 0.19) with the percent change in FMD.
conclusionAerobic exercise was beneficial for improving measures of vascular health but these were not statistically significant. The magnitude of change may be affected by the duration of DPN.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.