Evidence map›Paper›PMID 26784464›Full record

ArticleAntioxidants (Basel, Switzerland)2013

Antioxidant Constituents of Cotoneaster melanocarpus Lodd.

Veronika M D Holzer, Agnieszka D Lower-Nedza, Myagmar Nandintsetseg, Javzan Batkhuu, Adelheid H Brantner

Abstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Can Extracts from the Leaves and Fruits of theMolecules (Basel, Switzerland) · 2022
    Article
  4. Article
  5. An Overview of the GenusAntioxidants (Basel, Switzerland) · 2020
    Review
  6. Article
  7. Polyphenol-Rich Extracts fromMolecules (Basel, Switzerland) · 2018
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Veronika M D HolzerDepartment of Pharmacognosy, Institute of Pharmaceutical Sciences, Karl-Franzens University, Universitaetsplatz 4/I, Graz 8010, Austria. veronika.holzer@edu.uni-graz.at.
Agnieszka D Lower-NedzaDepartment of Pharmacognosy, Institute of Pharmaceutical Sciences, Karl-Franzens University, Universitaetsplatz 4/I, Graz 8010, Austria.
Myagmar NandintsetsegLaboratory of Bioorganic Chemistry and Pharmacognosy, Department of Biochemistry and Bioorganic Chemistry, School of Biology and Biotechnology, National University of Mongolia, P.O.B-617, Ulaanbaatar-46A, Mongolia. nandia0520@yahoo.com.
Javzan BatkhuuLaboratory of Bioorganic Chemistry and Pharmacognosy, Department of Biochemistry and Bioorganic Chemistry, School of Biology and Biotechnology, National University of Mongolia, P.O.B-617, Ulaanbaatar-46A, Mongolia. jbatkhuu@num.edu.mn.
Adelheid H BrantnerDepartment of Pharmacognosy, Institute of Pharmaceutical Sciences, Karl-Franzens University, Universitaetsplatz 4/I, Graz 8010, Austria. adelheid.brantner@uni-graz.at.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was the evaluation of the antioxidant capacity of Cotoneaster melanocarpus Lodd. and the identification of antioxidant active constituents of this plant. C. melanocarpus Lodd. is a shrub indigenous to Mongolia and used in Traditional Mongolian Medicine as a styptic. Before extraction, the plant material was separated into three parts: young sterile shoots, older stems and leaves. All these parts were extracted with water, methanol, ethyl acetate, dichloromethane and hexane, successively. The methanolic extract of the sterile shoots showed the highest antioxidant activity in the DPPH (2,2-diphenyl-1-picrylhydrazyl) radical scavenging assay (IC50 30.91 ± 2.97 µg/mL). This active extract was further analyzed with chromatographic methods. TLC fingerprinting and HPLC indicated the presence of the flavonol glycosides quercetin-3-O-rutinoside (rutin), quercetin-3-O-galactoside (hyperoside) and quercetin-3-O-glucoside (isoquercetin), ursolic acid as well as chlorogenic acid, neochlorogenic acid and cryptochlorogenic acid. The findings were substantiated with LC-MS. All identified compounds have antioxidant properties and therefore contribute to the radical scavenging activity of the whole plant.

Indexed as

antioxidantsCotoneaster melanocarpusDPPHHPLCLC-MSTLC

Identifiers

PMID26784464
PMCPMC4665513

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.