ReviewOncotarget2016
Stromal characteristics may hold the key to mammographic density: the evidence to date.
Review in Oncotarget, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 30 citations in OpenAlex.
- Transcriptomic Profile of Breast Tissue of Premenopausal Women Following Treatment with Progesterone Receptor Modulator: Secondary Outcomes of a Randomized Controlled Trial.International journal of molecular sciences · 2024Trial
- Associations of alcohol use with expression of stromal markers in benign breast biopsy samples.British journal of cancer · 2026Article
- Review
- Trace element imbalances in selenium and mercury in relation to mammographic density and breast cancer progression: a case‒control study.Scientific reports · 2025Article
- Mammographic density and breast cancer pathological subtypes by menopausal status and body mass index.Breast cancer research : BCR · 2025Article
- Pathological macroscopic evaluation of breast density versus mammographic breast density in breast cancer conserving surgery.European journal of obstetrics & gynecology and reproductive biology: X · 2023Article
- Associations of alcohol consumption with breast tissue composition.Breast cancer research : BCR · 2023Article
- Breast Tissue Chemistry Measured In Vivo In Healthy Women Correlate with Breast Density and Breast Cancer Risk.Journal of magnetic resonance imaging : JMRI · 2022Article
- Associations of Oral Contraceptives with Mammographic Breast Density in Premenopausal Women.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2022Article
- Use of Low-Dose Tamoxifen to Increase Mammographic Screening Sensitivity in Premenopausal Women.Cancers · 2021Article
- Stromal vapors for real-time molecular guidance of breast-conserving surgery.Scientific reports · 2020Article
- Breast Mammographic Density: Stromal Implications on Breast Cancer Detection and Therapy.Journal of clinical medicine · 2020Review
- A Longitudinal Study of the Association between Mammographic Density and Gene Expression in Normal Breast Tissue.Journal of mammary gland biology and neoplasia · 2019Article
- Exploring the prediction performance for breast cancer risk based on volumetric mammographic density at different thresholds.Breast cancer research : BCR · 2018Article
- Review of quantitative multiscale imaging of breast cancer.Journal of medical imaging (Bellingham, Wash.) · 2018Review
- TRIENNIAL LACTATION SYMPOSIUM/BOLFA: Dietary regulation of allometric ductal growth in the mammary glands.Journal of animal science · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
There is strong epidemiological data indicating a role for increased mammographic density (MD) in predisposing to breast cancer, however, the biological mechanisms underlying this phenomenon are less well understood. Recently, studies of human breast tissues have started to characterise the features of mammographically dense breasts, and a number of in-vitro and in-vivo studies have explored the potential mechanisms through which dense breast tissue may exert this tumourigenic risk. This article aims to review both the pathological and biological evidence implicating a key role for the breast stromal compartment in MD, how this may be modified and the clinical significance of these findings. The epidemiological context will be briefly discussed but will not be covered in detail.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.