Evidence map›Paper›PMID 26784137›Full record

Trial reportAnnals of the American Thoracic Society2016

Palliative Care for Patients Dying in the Intensive Care Unit with Chronic Lung Disease Compared with Metastatic Cancer.

Crystal E Brown, Ruth A Engelberg, Elizabeth L Nielsen, J Randall Curtis

Registry-linked trialAbstract readClinical Trial, Phase IIIMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Annals of the American Thoracic Society, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00685893 (An ICU Intervention to Improve End-of-Life Care), which is not on this map. Cited by 30 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00685893 phase3completednot on this map

An ICU Intervention to Improve End-of-Life Care

TypeinterventionalSponsorUniversity of WashingtonRan2003 to 2010Enrolled3,498ConditionsAny Disease Causing Death in the ICU or Within 24 Hours of Discharge From the ICUArmsEducation, Local Champions, Institution Feedback, Academic Detailing, Institutional Forms
3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Article
  6. Observational
  7. Review
  8. Article
  9. Health disparities and associated social determinants of health in interstitial lung disease: a narrative review.European respiratory review : an official journal of the European Respiratory Society · 2025
    Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Linear and logistic regression models: when to use and how to interpret them?Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia · 2023
    Article
  16. Article
  17. Article
  18. A scoping review of palliative care outcome measures in interstitial lung disease.European respiratory review : an official journal of the European Respiratory Society · 2021
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Crystal E BrownDivision of Pulmonary and Critical Care, Department of Medicine, Harborview Medical Center, University of Washington, Seattle, Washington.ORCID 0000-0002-1223-7422
Ruth A EngelbergDivision of Pulmonary and Critical Care, Department of Medicine, Harborview Medical Center, University of Washington, Seattle, Washington.
Elizabeth L NielsenDivision of Pulmonary and Critical Care, Department of Medicine, Harborview Medical Center, University of Washington, Seattle, Washington.
J Randall CurtisDivision of Pulmonary and Critical Care, Department of Medicine, Harborview Medical Center, University of Washington, Seattle, Washington.

Funding

Randomized trial of an interdisciplinary communication intervention to improve paR01NR005226 · NINR · UNIVERSITY OF WASHINGTON · PI CURTIS, J RANDALL, ENGELBERG, RUTH ANN · 1999 to 2012
$6.7M
NINR NIH HHS R01 NR005226
6 · The paper itself

Abstract

rationalePalliative care has been focused largely on patients with cancer, and yet patients with chronic lung diseases also have high morbidity and mortality. The majority of deaths in intensive care units (ICUs) follow decisions to withhold or withdraw life-sustaining treatments, suggesting that palliative care is critically important in this setting.

objectivesWe explored differences in receipt of elements of palliative care among patients with interstitial lung disease (ILD) and chronic obstructive pulmonary disease (COPD) who die in ICUs compared with patients with cancer.

methodsWe identified patients with COPD, ILD, or metastatic cancer who died in the ICUs of 15 Seattle-area hospitals between 2003 and 2008. We used robust multivariable logistic and linear regression to compare differences in receipt of elements of palliative care and length of stay. MEASUREMENTS AND MAIN

resultsCompared with patients with cancer, patients with COPD were more likely to receive cardiopulmonary resuscitation before death and patients with ILD were less likely to have documentation of pain assessment in the last day of life. Patients with ILD and COPD were less likely to have a do-not-resuscitate order in place at the time of death and less likely to have documentation of discussions about prognosis than patients with cancer. Patients with COPD had longer hospital lengths of stay, and patients with COPD and ILD had longer ICU lengths of stay.

conclusionsAmong patients who die in the ICU, patients with ILD and COPD receive fewer elements of palliative care and have longer lengths of stay than patients with cancer. These findings identify areas for improvement in caring for patients with chronic lung diseases. Clinical trial registered with www.clinicaltrials.gov (NCT00685893).

Indexed as

AgedAged, 80 and overFemaleHumansIntensive Care UnitsLength of StayLinear ModelsLogistic ModelsLung Diseases, InterstitialMaleMiddle AgedMultivariate AnalysisNeoplasms, Second PrimaryPalliative CarePulmonary Disease, Chronic ObstructiveResuscitation Orderschronic lung diseasechronic obstructive pulmonary diseaseinterstitial lung diseasemetastatic cancerpalliative care

Identifiers

PMID26784137
PMCPMC5018894

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.