Evidence map›Paper›PMID 26783965›Full record

ArticleNature communications2016

Iron Age and Anglo-Saxon genomes from East England reveal British migration history.

Stephan Schiffels, Wolfgang Haak, Pirita Paajanen, Bastien Llamas, Elizabeth Popescu, Louise Loe, Rachel Clarke, Alice Lyons, Richard Mortimer, Duncan Sayer and 3 more

Abstract read
In one paragraph

Article in Nature communications, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 90 papers.

0numbers the graph read from it
0cells of the map it votes in
90citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

90 citing papers in PubMed.

  1. Article
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  4. Pan-African model explainsbioRxiv : the preprint server for biology · 2026
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  5. The Genomic Legacy of the Norman Conquest in Rural England.bioRxiv : the preprint server for biology · 2026
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  6. Article
  7. Global patterns of natural selection inferred using ancient DNA.bioRxiv : the preprint server for biology · 2026
    Article
  8. Article
  9. Article
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  12. Article
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  19. Capturing the fusion of two ancestries and kinship structures in Merovingian Flanders.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  20. Article

30 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors.

Stephan SchiffelsWellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, UK.
Wolfgang HaakAustralian Centre for Ancient DNA, School of Biological Sciences and The Environment Institute, University of Adelaide, Adelaide, South Australia 5005, Australia.
Pirita PaajanenWellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, UK.
Bastien LlamasAustralian Centre for Ancient DNA, School of Biological Sciences and The Environment Institute, University of Adelaide, Adelaide, South Australia 5005, Australia.
Elizabeth PopescuOxford Archaeology East, 15 Trafalgar Way, Bar Hill, Cambridge CB23 8SQ, UK.
Louise LoeOxford Archaeology South, Janus House, Osney Mead, Oxford OX2 0ES, UK.
Rachel ClarkeOxford Archaeology East, 15 Trafalgar Way, Bar Hill, Cambridge CB23 8SQ, UK.
Alice LyonsOxford Archaeology East, 15 Trafalgar Way, Bar Hill, Cambridge CB23 8SQ, UK.
Richard MortimerOxford Archaeology East, 15 Trafalgar Way, Bar Hill, Cambridge CB23 8SQ, UK.
Duncan SayerSchool of Forensic and Applied Sciences, University of Central Lancashire, Preston PR1 2HE, UK.
Chris Tyler-SmithWellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, UK.
Alan CooperAustralian Centre for Ancient DNA, School of Biological Sciences and The Environment Institute, University of Adelaide, Adelaide, South Australia 5005, Australia.
Richard DurbinWellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, UK.

Funding

Wellcome Trust 098051
6 · The paper itself

Abstract

British population history has been shaped by a series of immigrations, including the early Anglo-Saxon migrations after 400 CE. It remains an open question how these events affected the genetic composition of the current British population. Here, we present whole-genome sequences from 10 individuals excavated close to Cambridge in the East of England, ranging from the late Iron Age to the middle Anglo-Saxon period. By analysing shared rare variants with hundreds of modern samples from Britain and Europe, we estimate that on average the contemporary East English population derives 38% of its ancestry from Anglo-Saxon migrations. We gain further insight with a new method, rarecoal, which infers population history and identifies fine-scale genetic ancestry from rare variants. Using rarecoal we find that the Anglo-Saxon samples are closely related to modern Dutch and Danish populations, while the Iron Age samples share ancestors with multiple Northern European populations including Britain.

Indexed as

ArchaeologyEmigration and ImmigrationEnglandGenetics, PopulationGenome, HumanHumansUnited KingdomWhite People

Identifiers

PMID26783965
PMCPMC4735688

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.