ArticleJournal of diabetes research2016
High Frequency of Diabetic Ketoacidosis in Children with Newly Diagnosed Type 1 Diabetes.
Article in Journal of diabetes research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 67 citations in OpenAlex.
- Changes in the clinical picture of type 1 diabetes in children at diagnosis: past hopelessness in face of diabetic ketoacidosis vs. current hope for prevention and cure in the early stages of diabetes with developing treatment possibilities.Pediatric endocrinology, diabetes, and metabolism · 2025Article
- Incidence and Predictors of Diabetic Keto-acidosis Among Children Under 15 Years At Central Ethiopia Public Hospital A Retrospective Cohort Study.Clinical medicine insights. Pediatrics · 2025Article
- Factors associated with severe diabetic ketoacidosis in patients diagnosed with type 1 diabetes: a decade-long cross-sectional analysis.The Journal of international medical research · 2024Article
- Risk Factors and Laboratory Findings Associated With Diabetic Ketoacidosis in Hospitalized Pediatric Patients.Cureus · 2022Article
- Incidence of Type 1 diabetes and factors associated with presence and severity of ketoacidosis at onset in children.Acta bio-medica : Atenei Parmensis · 2022Article
- Article
- Is diabetic ketoacidosis a good predictor of 5-year metabolic control in children with newly diagnosed type 1 diabetes?BMC endocrine disorders · 2021Article
- A Multicenter Survey of Type I Diabetes Mellitus in Chinese Children.Frontiers in endocrinology · 2021Article
- Incidence and predictors of diabetic ketoacidosis among children with diabetes in west and east Gojjam zone referral hospitals, northern Ethiopia, 2019.Italian journal of pediatrics · 2020Article
- The Effects of Prehospital Care on Outcome in Pediatric Diabetic KetoacidosisJournal of clinical research in pediatric endocrinology · 2020Article
- Level of awareness of diabetic ketoacidosis among diabetes mellitus patients in Riyadh.Journal of family medicine and primary care · 2020Article
- Insulin therapy is not associated with improved clinical outcomes in critically ill infants with stress hyperglycemia.Experimental and therapeutic medicine · 2019Article
- [Study of acute inaugural ketosis-prone diabetes in a Hospital in Central-Eastern Tunisian].The Pan African medical journal · 2018Article
- Diabetic Ketoacidosis Severity at Diagnosis and Glycaemic Control in the First Year of Childhood Onset Type 1 Diabetes-A Longitudinal Cohort Study.International journal of environmental research and public health · 2017Article
- Efficacy and Safety of Low Dose Insulin Infusion against Standard Dose Insulin Infusion in Children with Diabetic Ketoacidosis- An Open Labelled Randomized Controlled Trial.Indian journal of endocrinology and metabolismArticle
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimThe aim of this study was to evaluate the incidence of diabetic ketoacidosis in children and adolescents with newly diagnosed type 1 diabetes in 2006-2007 and 2013-2014.
methodThe study group consisted of 426 children aged 0-18 years with type 1 diabetes onset admitted to our hospital in 2006-2007 (group A) and 2013-2014 (group B). The study comprised the analysis of medical and laboratory records from patients' medical charts and the electronic database.
resultsThere was no difference between groups A and B in the percentage of children admitted with diabetic ketoacidosis (25% versus 28%, resp., P = 0.499). Among children with diabetic ketoacidosis, severe metabolic decompensation (pH < 7.1) appeared in similar frequency in groups A and B (28% versus 30%, resp., P = 0.110). In group B, children with diabetic ketoacidosis were statistically younger compared to patients without ketoacidosis (P = 0.015) and had higher HbA1c levels (P = 0.006). In both groups, a 2-fold increase in diabetic ketoacidosis was noted in children under the age of 3, compared to overall frequency.
conclusionNo decrease in diabetic ketoacidosis has been noted in the recent years. Although the prevalence and severity of diabetic ketoacidosis remain stable, they are unacceptably high. The youngest children are especially prone to ketoacidosis.
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