Evidence map›Paper›PMID 26783491›Full record

ArticleCase reports in transplantation2015

Gastrointestinal Bleeding and Diffuse Skin Thickening as Kaposi Sarcoma Clinical Presentation.

Sara Querido, Henrique Silva Sousa, Tiago Assis Pereira, Rita Birne, Patrícia Matias, Cristina Jorge, André Weigert, Teresa Adragão, Margarida Bruges, Domingos Machado

Open access · goldAbstract read
In one paragraph

Article in Case reports in transplantation, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Sara QueridoDepartment of Nephrology, Centro Hospitalar do Médio Tejo, Avenida Xanana Gusmão, Apartado 45, 2350-754 Torres Novas, Portugal.
Henrique Silva SousaDepartment of Nephrology, Centro Hospitalar de Lisboa Ocidental, Avenida Professor Reinaldo dos Santos, 2790-134 Carnaxide, Portugal.
Tiago Assis PereiraDepartment of Nephrology, Centro Hospitalar de Lisboa Ocidental, Avenida Professor Reinaldo dos Santos, 2790-134 Carnaxide, Portugal.
Rita BirneDepartment of Nephrology, Centro Hospitalar de Lisboa Ocidental, Avenida Professor Reinaldo dos Santos, 2790-134 Carnaxide, Portugal.
Patrícia MatiasDepartment of Nephrology, Centro Hospitalar de Lisboa Ocidental, Avenida Professor Reinaldo dos Santos, 2790-134 Carnaxide, Portugal.
Cristina JorgeDepartment of Nephrology, Centro Hospitalar de Lisboa Ocidental, Avenida Professor Reinaldo dos Santos, 2790-134 Carnaxide, Portugal.
André WeigertDepartment of Nephrology, Centro Hospitalar de Lisboa Ocidental, Avenida Professor Reinaldo dos Santos, 2790-134 Carnaxide, Portugal.
Teresa AdragãoDepartment of Nephrology, Centro Hospitalar de Lisboa Ocidental, Avenida Professor Reinaldo dos Santos, 2790-134 Carnaxide, Portugal.
Margarida BrugesDepartment of Nephrology, Centro Hospitalar de Lisboa Ocidental, Avenida Professor Reinaldo dos Santos, 2790-134 Carnaxide, Portugal.
Domingos MachadoDepartment of Nephrology, Centro Hospitalar de Lisboa Ocidental, Avenida Professor Reinaldo dos Santos, 2790-134 Carnaxide, Portugal.
Centro Hospitalar de Lisboa Ocidental · PTCentro Hospitalar do Porto · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 56-year-old African patient received a kidney from a deceased donor with 4 HLA mismatches in April 2013. He received immunosuppression with basiliximab, tacrolimus, mycophenolate mofetil, and prednisone. Immediate diuresis and a good allograft function were soon observed. Six months later, the serum creatinine level increased to 2.6 mg/dL. A renal allograft biopsy revealed interstitial fibrosis and tubular atrophy grade II. Toxicity of calcineurin inhibitor was assumed and, after a switch for everolimus, renal function improved. However, since March 2014, renal function progressively deteriorated. A second allograft biopsy showed no new lesions. Two months later, the patient was admitted due to anuria, haematochezia with anaemia, requiring 5 units of packed red blood cells, and diffuse skin thickening. Colonoscopy showed haemorrhagic patches in the colon and the rectum; histology diagnosis was Kaposi sarcoma (KS). A skin biopsy revealed cutaneous involvement of KS. Rapid clinical deterioration culminated in death in June 2014. This case is unusual as less than 20 cases of KS with gross gastrointestinal bleeding have been reported and only 6 cases had the referred bleeding originating in the lower gastrointestinal tract. So, KS should be considered in differential diagnosis of gastrointestinal bleeding in some kidney transplant patients.

Identifiers

PMID26783491
PMCPMC4689922
OpenAlexW2221071597

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.