Evidence map›Paper›PMID 26783384›Full record

ArticleMediators of inflammation2015

Chronic Comorbidities Contribute to the Burden and Costs of Persistent Asthma.

Paula Kauppi, Miika Linna, Juha Jantunen, Jaana E Martikainen, Tari Haahtela, Anna Pelkonen, Mika Mäkelä

Open access · goldAbstract read
In one paragraph

Article in Mediators of inflammation, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 2 pooled it
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 43 citations in OpenAlex.

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  13. Diabetes Mellitus Is Associated with Worse Outcome in Patients Hospitalized for Asthma.The journal of allergy and clinical immunology. In practice · 2021
    Article
  14. Impact of comorbid conditions on asthmatic adults and children.NPJ primary care respiratory medicine · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Paula KauppiUniversity of Helsinki, Helsinki University Central Hospital, Respiratory Diseases and Allergology, Inflammation Center, Skin and Allergy Hospital, P.O. Box 160, 00029 Helsinki, Finland.ORCID 0000-0002-1065-330X
Miika LinnaDepartment of Industrial Engineering and Management, Aalto University, P.O. Box 15500, 00076 Aalto, Finland.
Juha JantunenSouth Karelia Allergy and Environment Institute, Lääkäritie 15, 55330 Tiuruniemi, Finland.
Jaana E MartikainenSocial Insurance Institution, Research Department, P.O. Box 450, 00101 Helsinki, Finland.
Tari HaahtelaUniversity of Helsinki, Helsinki University Central Hospital, Respiratory Diseases and Allergology, Inflammation Center, Skin and Allergy Hospital, P.O. Box 160, 00029 Helsinki, Finland.
Anna PelkonenUniversity of Helsinki, Helsinki University Central Hospital, Pediatric Diseases and Allergology, Inflammation Center, Skin and Allergy Hospital, P.O. Box 160, 00029 Helsinki, Finland.
Mika MäkeläUniversity of Helsinki, Helsinki University Central Hospital, Pediatric Diseases and Allergology, Inflammation Center, Skin and Allergy Hospital, P.O. Box 160, 00029 Helsinki, Finland.
University of Helsinki · FIAalto University · FIAllergy and Asthma Federation · FISocial Insurance Institution · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe aimed to study the prevalence of chronic comorbidities in asthma patients and the costs of health care use associated with asthma with comorbidities. MATERIAL AND

methodsWe analysed the prevalence of the four most common chronic diseases in asthma patients in 2008-2014 in Finland. Prevalence of coronary artery disease, diabetes and dyslipidaemia, hypertension, epilepsy, inflammatory bowel disease, rheumatic diseases, and severe psychiatric disease was studied by register of the Social Insurance Institution of Finland. The costs of health care services were collected from the registries maintained by the National Institute for Health and Welfare (THL).

resultsPrevalence of asthma was 4.6% in 2014. Diabetes was among the four most common comorbidities in all the age groups. The other common comorbidities were hypertension (≥46 years; 12.9-37.6%), severe psychiatric disorders (age groups of 16-59 years; 1.4-3.5%), and ischaemic heart disease (≥60 years; 10-25%). In patients with both asthma and diabetes, the costs of hospitalization were approximately 169% compared with patients with asthma alone.

conclusionsPrevalence of asthma increases by tenfold when aging. The comorbidity diversity and rate are age-dependent. Prevalence of diabetes as comorbidity in asthma has increased. Costs of hospitalizations in asthma approximately double with chronic comorbidities.

Indexed as

AdolescentAdultAgedAged, 80 and overAsthmaCardiovascular DiseasesChildChild, PreschoolComorbidityCosts and Cost AnalysisDiabetes MellitusEpilepsyFemaleFinlandHumansInfant

Identifiers

PMID26783384
PMCPMC4691464
OpenAlexW2192575346

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.