ArticleInfection2016
Fusobacterium nucleatum infections: clinical spectrum and bacteriological features of 78 cases.
Article in Infection, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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Who cites it
28 citing papers in PubMed, 43 citations in OpenAlex.
- Infections Caused by Fusobacterium Species: Microbiology, Clinical Syndromes and Management: A Narrative Review.Infectious diseases and therapy · 2026Review
- Odontogenic Brain Abscess in a Hereditary Haemorrhagic Telangiectasia (HHT) Patient: Case Report with a Comprehensive Literature Review.Tropical medicine and infectious disease · 2026Article
- A rare brain abscess caused by co-infection with Fusobacterium nucleatum and Actinomyces meyeri : Case report and a literature review.Wiener medizinische Wochenschrift (1946) · 2026Article
- Reprogramming of pathogenic strategies inFrontiers in cellular and infection microbiology · 2026Article
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- Bacterial translocation signatures and subgingival microbiome in individuals with periodontitis.Clinical oral investigations · 2025Article
- Pyogenic liver abscess and sepsis caused by mixed anaerobic bacteria in an immunocompetent adult: a case report.Frontiers in medicine · 2025Article
- Fusobacterium nucleatum-Induced Empyema Masquerading as Lung Cancer: A Diagnostic Challenge.Cureus · 2024Article
- Retrospective study on clinical value and optimal use of [Scientific reports · 2024Article
- Sternoclavicular Septic Arthritis Caused by Parvimonas micra and Fusobacterium nucleatum Infection with Intra-articular Corticosteroid Administration.Internal medicine (Tokyo, Japan) · 2024Article
- Ruptured intraventricular brain abscesses due to Fusobacterium nucleatum with obstructive hydrocephalus: illustrative case.Journal of neurosurgery. Case lessons · 2023Article
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- Case report: Two case reports of cryptogenic brain abscess caused byFrontiers in neuroscience · 2023Article
- [NLRC4 plays a regulatory role in F. nucleatum-induced pyroptosis in macrophages].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2022Article
- Fusobacterium nucleatum promotes the development of acute liver failure by inhibiting the NADGut pathogens · 2022Article
- Educational case: Brain abscess.Academic pathology · 2022Article
- Case report: Meningitis and intracranial aneurysm caused by mixed infection of oral microflora dominated by anaerobes.Frontiers in neurology · 2022Article
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- Article
- Glycan cross-feeding supports mutualism between Fusobacterium and the vaginal microbiota.PLoS biology · 2020Article
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeFew series describe the clinical spectrum of Fusobacterium spp. infections. Among them, fewer discuss F. nucleatum, even though there are many clinical cases.
methodsWe performed a retrospective study over 8 years (from 2007 to 2014) in Limoges University Hospital, France, to assess clinical and bacteriological aspects of infections due to F. nucleatum.
resultsEighty-one patients with F. nucleatum positive cultures were included in this study, irrespective of sample origin. Abscesses (n = 43), bacteraemia (n = 18) and bone infections (n = 8) were the most common types of infections, Abscesses were found in various organs (mostly skin, brain, pleura, liver). Co-morbidities were found in 38 patients (47 %) with neoplasia, diabetes, and alcoholism and history of smoking. There were more neoplasms in patients with bacteraemia than in patients with abscesses (p = 0.007). In 51 cases (65.4 %), infection was polymicrobial, either during bacteraemia or abscesses. Main associations were with Streptococcus spp., Peptostreptococcus spp. and/or Prevotella spp. The sources of infection, when found, were either dental or gastrointestinal. All isolates were susceptible to penicillin, clindamycin and metronidazole.
conclusionsInfections involving F. nucleatum are uncommon and potentially severe, with many abscesses requiring surgery. Bacteraemia was mainly associated with co-morbidities such as cancer. Polymicrobial infections were very common and there is probably interaction and/or synergy between F. nucleatum and some other commensal bacteria to cause infections and abscesses.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.