Evidence map›Paper›PMID 26783021›Full record

ArticleJournal of feline medicine and surgery2017

Serum acute phase proteins in Dirofilaria immitis and Wolbachia seropositive cats.

Ana C Silvestre-Ferreira, Lisete Vieira, Hugo Vilhena, Jose J Cerón, Asta Tvarijonaviciute, José A Montoya-Alonso, Elena Carretón, Josep Pastor

Open access · greenAbstract readEvaluation Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of feline medicine and surgery, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Guideline
  2. Article
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  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Ana C Silvestre-Ferreira1 Department of Veterinary Sciences, University of Trás-os-Montes and Alto Douro, Vila Real, Portugal.
Lisete Vieira1 Department of Veterinary Sciences, University of Trás-os-Montes and Alto Douro, Vila Real, Portugal.
Hugo Vilhena2 Animal and Veterinary Research Centre (CECAV), University of Trás-os-Montes and Alto Douro, Vila Real, Portugal.
Jose J Cerón5 Interdisciplinary Laboratory of Clinical Analysis (Interlab-UMU), Veterinary School, Campus of Excellence Mare Nostrum, University of Murcia, Espinardo, Murcia, Spain.
Asta Tvarijonaviciute5 Interdisciplinary Laboratory of Clinical Analysis (Interlab-UMU), Veterinary School, Campus of Excellence Mare Nostrum, University of Murcia, Espinardo, Murcia, Spain.
José A Montoya-Alonso7 Research Institute of Biomedical and Health Sciences (IUIBS), Faculty of Veterinary Medicine, University of Las Palmas de Gran Canaria, Arucas, Las Palmas, Spain.
Elena Carretón7 Research Institute of Biomedical and Health Sciences (IUIBS), Faculty of Veterinary Medicine, University of Las Palmas de Gran Canaria, Arucas, Las Palmas, Spain.
Josep Pastor6 Department of Animal Medicine and Surgery, Autonomous University of Barcelona, Barcelona, Spain.
Universidad de Las Palmas de Gran Canaria · ESUniversidad de Murcia · ESUniversity of Trás-os-Montes and Alto Douro · PTCentro Hospitalar do Baixo Vouga · PTUniversitat Autònoma de Barcelona · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives The aim of this study was to characterise the response of acute phase proteins (APPs) in cats seropositive for Dirofilaria immitis and to its endosymbiont bacterium Wolbachia. Methods The APPs serum amyloid A (SAA), haptoglobin (Hp) and ceruloplasmin (Cp) were measured in 25 seropositive cats and in 16 healthy seronegative cats. Results SAA and Cp concentrations were significantly higher in animals with D immitis seropositivity that exhibited clinical signs related to the disease, and Hp was elevated in all D immitis-seropositive animals. There was no significant correlation between APPs and D immitis or Wolbachia species antibody titres. Conclusions and relevance An association between feline seropositivity to D immitis and APP response was demonstrated. Increases in serum SAA and Cp concentrations were related to D immitis-associated clinical signs, whereas Hp increased in all seropositive animals.

Indexed as

Acute-Phase ProteinsAnimalsAntibodies, BacterialCat DiseasesCatsDirofilaria immitisDirofilariasisFemaleMalePredictive Value of TestsSerologic TestsWolbachiaAcute-Phase ProteinsAntibodies, Bacterial

Identifiers

PMID26783021
PMCPMC11128812
OpenAlexW2339456742

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.