Evidence map›Paper›PMID 26782820›Full record

SynthesisThe American journal of gastroenterology2016

Validated Scales for Colon Cleansing: A Systematic Review.

Robin Parmar, Myriam Martel, Alaa Rostom, Alan N Barkun

7 registry-linked trialsAbstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in The American journal of gastroenterology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 7 registered trials, which are not on this map. Cited by 82 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
82citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02955901 nacompletednot on this mapstarted 2017, after this paper: background citation

A 3-day Versus 1-day Low Residue Diet to Improve Colonoscopy Preparation Result and Patient Tolerability: A Prospective, Randomized, Single-blinded, Controlled Trial

TypeinterventionalSponsorPortuguese Oncology Institute, CoimbraRan2017 to 2019Enrolled412ConditionsColon Disease, Colonic NeoplasmsArms3 day low residue diet prior to the colonoscopy, 1 day low residue diet prior to the colonoscopy
NCT03410524 phase3completednot on this mapstarted 2018, after this paper: background citation

Simethicone Pretreatment With Low-volume Polyethylene Glycol-3350 and Bisacodyl in an Effort to Improve Bowel Wall Visualization During Colonoscopy

TypeinterventionalSponsorUniversity of Nevada, RenoRan2018 to 2018Enrolled250ConditionsColonoscopyArmsSimethicone Solution, Water
NCT03650725 completednot on this mapstarted 2018, after this paper: background citation

Evaluation of Information Provided to Patients Provided About Bowel Preparation for Morning Colonoscopy

TypeobservationalSponsorHarminder SinghRan2018 to 2023Enrolled1,000ConditionsColonoscopy, Patient ComplianceArmsMandatory Split bowel preparation
NCT03816774 nacompletednot on this mapstarted 2019, after this paper: background citation

Effect of Adding Simethicone to a Split Regimen of Polyethylene Glycol for Bowel Preparation in a Colorectal Cancer Screening Colonoscopy Setting: an Endoscopist-blinded Randomized Controlled Trial

TypeinterventionalSponsorPortuguese Oncology Institute, CoimbraRan2019 to 2022Enrolled412ConditionsColo-rectal Cancer, Colonic NeoplasmsArmsPEG split-dose and simethicone
NCT05512793 nacompletednot on this mapstarted 2023, after this paper: background citation

PolyDeep Advance 2: Clinical Validation of PolyDeep. Randomized Clinical Trial with a Tandem Colonoscopy Design.

TypeinterventionalSponsorFundacin Biomedica Galicia SurRan2023 to 2023Enrolled260ConditionsColorectal CancerArmsStandard technique First colonoscopy without PolyDeep, Combination technique First colonoscopy with PolyDeep
NCT05513261 nacompletednot on this mapstarted 2023, after this paper: background citation

PolyDeep Advance 3: Randomized Clinical Trial Comparing High Definition Colonoscopy With PolyDeep Assisted High Definition Colonoscopy.

TypeinterventionalSponsorFundacin Biomedica Galicia SurRan2023 to 2024Enrolled857ConditionsColorectal CancerArmsHigh definition colonoscopy (standard colonoscopy) in Adenoma Detection Rate, PolyDeep assisted high definition colonoscopy (CAD system) in Adenoma Detection Rate
NCT05514301 nacompletednot on this mapstarted 2023, after this paper: background citation

Polydeep Advance I: Prospective Diagnostic Tests Trial with a Paired Study Design

TypeinterventionalSponsorFundacin Biomedica Galicia SurRan2023 to 2023Enrolled205ConditionsColorectal CancerArmsSensitivity of Polydeep vs high experienced endoscopists for colorectal polyp detection
3 · Its place in the literature

Who cites it

82 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Factors Associated With the Overuse of Colorectal Cancer Screening: A Systematic Review.American journal of medical quality : the official journal of the American College of Medical Quality
    Pooled it
  4. Trial
  5. Trial
  6. Trial
  7. Trial
  8. Trial
  9. Trial
  10. Review
  11. Article
  12. The Clinical Importance of Adequate Bowel Preparation.Alimentary pharmacology & therapeutics · 2026
    Review
  13. Review
  14. Article
  15. Article
  16. Article
  17. Research progress on intestinal preparation before colonoscopy.World journal of gastrointestinal endoscopy · 2025
    Review
  18. Article
  19. Article
  20. Review

22 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Robin ParmarDivision of Gastroenterology, McGill University Health Center, McGill University, Montreal, Quebec, Canada.
Myriam MartelDivision of Gastroenterology, McGill University Health Center, McGill University, Montreal, Quebec, Canada.
Alaa RostomDivision of Gastroenterology, The Ottawa Hospital and University of Ottawa, Ottawa, Ontario, Canada.
Alan N BarkunDivision of Gastroenterology, McGill University Health Center, McGill University, Montreal, Quebec, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesBowel cleanliness is a critical determinant of colonoscopy quality, mandating its standardized assessment, yet bowel preparation scales have been variably validated. The objective of this study was to assess validity and reliability of existing bowel preparation scales.

methodsA systematic review of literature from January 1980 to January 2015 was performed. Main outcomes of this study are face, content, construct, and criterion validity, and inter- and intra-observer reliability measured by associations, interclass correlations (ICC) or κ-coefficients.

resultsFourteen citations assessed seven scales. The Aronchick Scale, showed fair-to-substantial inter-observer reliability (ICC=0.31-0.76), and was the reference for subsequent validity testing. The Ottawa Bowel Preparation Quality Scale revealed superior inter-observer reliability (ICC=0.94). Five studies assessed the Boston Bowel Preparation Scale (BBPS). Increasing BBPS scores were associated with polyp detection (left colon: odds ratio (OR)=2.58 (1.34; 4.98), right colon: OR=1.6 (1.01; 2.55), less repeat colonoscopies (cutoff of 5, P<0.001), and shorter insertion/withdrawal times (P<0.001), while displaying substantial to excellent inter- and intra-observer reliability (ICC=0.74-0.91). Criterion validity of the Harefield Cleansing Scale (HCS) yielded slight-to-moderate expert-investigator agreement (ICC=0.15-0.46); HCS grades were not discriminant for adenoma detection. Inter- and intra-observer reliabilities were fair-to-moderate (ICC=0.46 (0.37; 0.54) and κ=0.28, respectively). The Chicago Bowel Preparation Scale displayed excellent inter-observer reliability (Pearson's r=0.84 (0.79; 0.88)), yet has been less studied.

conclusionsTo conclude, all the published scales displayed limitations. The BBPS is the most thoroughly validated scale and should be used in a clinical setting. Between-scale comparisons for repeat colonoscopy time interval, ease, and pertinence of use for auditing are needed.

Indexed as

ColonAdenomaCatharticsColonoscopyColorectal NeoplasmsHumansReproducibility of ResultsCathartics

Identifiers

PMID26782820

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

and 1 more above

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.