Evidence map›Paper›PMID 26782118›Full record

ArticleCardiovascular research2016

PITX2: a master regulator of cardiac channelopathy in atrial fibrillation?

Na Li, Dobromir Dobrev, Xander H T Wehrens

Abstract readEditorialComment
PubMed Full text at PMC Publisher
In one paragraph

Article in Cardiovascular research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. The Evolving Story in the Genetic Analysis for Heart Failure.Frontiers in cardiovascular medicine · 2021
    Review
  4. Article
  5. Review
  6. Review
  7. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Na LiCardiovascular Research Institute, Baylor College of Medicine, Houston, TX, USA Department of Molecular Physiology and Biophysics, Baylor College of Medicine, Houston, TX, USA.
Dobromir DobrevInstitute of Pharmacology, West German Heart and Vascular Center, Faculty of Medicine, University Duisburg-Essen, Essen, Germany.
Xander H T WehrensCardiovascular Research Institute, Baylor College of Medicine, Houston, TX, USA Department of Molecular Physiology and Biophysics, Baylor College of Medicine, Houston, TX, USA Department of Medicine (Cardiology), Baylor College of Medicine, Houston, TX, USA Department of Pediatrics, Baylor College of Medicine, One Baylor Plaza, BCM 335, Houston, TX 77030, USA wehrens@bcm.edu.

Funding

Ryanodine receptor regulation in post-operative atrial fibrillationR01HL089598 · NHLBI · BAYLOR COLLEGE OF MEDICINE · PI WEHRENS, XANDER H.T. · 2007 to 2022
$6.5M
Regulation of Sarcoplasmic Reticulum Calcium Release in Heart FailureR01HL091947 · NHLBI · BAYLOR COLLEGE OF MEDICINE · PI WEHRENS, XANDER H.T. · 2009 to 2019
$3.2M
Determining the Role of Junctophilin-2 in Cardiac DiseaseR01HL117641 · NHLBI · BAYLOR COLLEGE OF MEDICINE · PI WEHRENS, XANDER H.T. · 2014 to 2017
$2.3M
Development of novel compounds for the treatment of atrial fibrillationR41HL129570 · NHLBI · ELEX BIOTECH, LLC · PI WEHRENS, XANDER H.T. · 2015 to 2015
$428k
NHLBI NIH HHS R01 HL089598NHLBI NIH HHS R01-HL089598NHLBI NIH HHS R01 HL091947NHLBI NIH HHS R01-HL091947NHLBI NIH HHS R01 HL117641NHLBI NIH HHS R01-HL117641NHLBI NIH HHS R41 HL129570NHLBI NIH HHS R41-HL129570
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Atrial FibrillationChannelopathiesCardiovascular DiseasesHomeodomain ProteinsHumansTranscription FactorsHomeodomain ProteinsTranscription Factors

Identifiers

PMID26782118
PMCPMC4752046

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.