Evidence map›Paper›PMID 26782051›Full record

ArticleMolecular psychiatry2016

Molecular systems evaluation of oligomerogenic APP(E693Q) and fibrillogenic APP(KM670/671NL)/PSEN1(Δexon9) mouse models identifies shared features with human Alzheimer's brain molecular pathology.

B Readhead, J-V Haure-Mirande, B Zhang, V Haroutunian, S Gandy, E E Schadt, J T Dudley, M E Ehrlich

Abstract readPublished Erratum
In one paragraph

Article in Molecular psychiatry, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. rTg-D: A novel transgenic rat model of cerebral amyloid angiopathy Type-2.Cerebral circulation - cognition and behavior · 2022
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

B Readhead
J-V Haure-Mirande
B Zhang
V Haroutunian
S Gandy
E E Schadt
J T Dudley
M E Ehrlich

Funding

VESICULAR LOCALIZATION AND FUNCTION OF PRESENILIN 1 FRAGMENTP50AG005138 · NIA · MOUNT SINAI SCHOOL OF MEDICINE OF NYU · PI SCHIMMING, CORBETT · 1985 to 2019
$37.9M
Integrative Network Biology Approaches to Identify, Characterize and Validate Molecular Subtypes in Alzheimer's DiseaseU01AG046170 · NIA · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI WANG, MINGHUI, ZHANG, BIN · 2013 to 2022
$26.0M
Network Based Predictive Drug Discovery for Alzheimer's DiseaseR34AG049649 · NIA · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI DUDLEY, JOEL THOMAS, GANDY, SAMUEL E. · 2014 to 2014
$366k
NIA NIH HHS R34 AG049649NIA NIH HHS U01 AG046170
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID26782051
PMCPMC6783804

What OpenQuestion holds

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LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.