Evidence map›Paper›PMID 26782040›Full record

ArticleProbiotics and antimicrobial proteins2012

Probiotic Activity of a Bacterial Strain Isolated from Ancient Permafrost Against Salmonella Infection in Mice.

O Fursova, V Potapov, A Brouchkov, G Pogorelko, G Griva, N Fursova, S Ignatov

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In one paragraph

Article in Probiotics and antimicrobial proteins, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

O FursovaLomonosov Moscow State University, Moscow, Russia. oksfursova@yandex.ru.
V PotapovState Research Center for Applied Microbiology and Biotechnology (SRCAMB), Obolensk, Russia.
A BrouchkovLomonosov Moscow State University, Moscow, Russia.
G PogorelkoNI Vavilov Institute of General Genetics, Russian Academy of Sciences, Moscow, Russia.
G GrivaTyumen Scientific Centre, Siberian Branch of Russian Academy of Science, Tyumen, Russia.
N FursovaState Research Center for Applied Microbiology and Biotechnology (SRCAMB), Obolensk, Russia.
S IgnatovState Research Center for Applied Microbiology and Biotechnology (SRCAMB), Obolensk, Russia.
State Research Center for Applied Microbiology and Biotechnology · RULomonosov Moscow State University · RUIowa State University · USSiberian Branch of the Russian Academy of Sciences · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bacillus cereus strain F, collected from relict permafrost located in Siberia, was analyzed for probiotic activity in the mouse Salmonella enterica model. Viable bacterial cells were found in frozen soils taken at Mammoth Mountain in Yakutia from a depth below the level of seasonal thawing. Geological data indicated the absence of a thawing within millions of years of deposited soils, which helped to ensure the ancient origin of our sample. According to DNA analysis, bacterial cells collected from the relict permafrost appeared to be B. cereus strain F. The morphology of these bacteria was analyzed using atomic force microscopy. B. cereus strain F was assessed as a nonpathogenic bacterium by evaluation of its pathogenicity. A S. enterica model is described in mice after per oral inoculation and serves as a model for the human carrier state. Using this model, probiotic activity by the bacterial strain isolated from the ancient permafrost has been shown against Salmonella infection in mice.

Indexed as

Ancient permafrostBacillus cereusMouse modelProbiotic activitySalmonella infection

Identifiers

PMID26782040
OpenAlexW2003170473

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.