ArticleFEMS microbiology letters2016
Using whole-genome sequencing to determine appropriate streptomycin epidemiological cutoffs for Salmonella and Escherichia coli.
Article in FEMS microbiology letters, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed.
- Shotgun proteomics for biomarker discovery in microbial pathogens and allergens in food: a review.Frontiers in bioengineering and biotechnology · 2026Review
- Conventionally Reared Wallon Meat Lambs Carry Transiently Multi-Drug-ResistantAnimals : an open access journal from MDPI · 2024Article
- Comparison of genotypic and phenotypic antimicrobial resistance profiles ofJournal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc · 2024Article
- Antimicrobial resistance studies in staphylococci and streptococci isolated from cows with mastitis in Argentina.Journal of veterinary science · 2022Article
- A National Antimicrobial Resistance Monitoring System Survey of Antimicrobial-Resistant Foodborne Bacteria Isolated from Retail Veal in the United States.Journal of food protection · 2021Article
- High-Resolution Genomic Comparisons withinApplied and environmental microbiology · 2021Article
- Antimicrobial Susceptibility Patterns and Wild-Type MIC Distributions of Anaerobic Bacteria at a German University Hospital: A Five-Year Retrospective Study (2015-2019).Antibiotics (Basel, Switzerland) · 2020Article
- Systematic Evaluation of Whole Genome Sequence-Based Predictions ofFrontiers in microbiology · 2020Article
- Prevalence and distribution of antimicrobial resistance determinants of Escherichia coli isolates obtained from meat in South Africa.PloS one · 2020Article
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- Population Dynamics ofApplied and environmental microbiology · 2019Article
- Validating the AMRFinder Tool and Resistance Gene Database by Using Antimicrobial Resistance Genotype-Phenotype Correlations in a Collection of Isolates.Antimicrobial agents and chemotherapy · 2019Article
- Emergence of Multidrug-Resistant Salmonella enterica Serovar Goldcoast Strains in Taiwan and International Spread of the ST358 Clone.Antimicrobial agents and chemotherapy · 2019Article
- Comparative Genomic Analysis of Virulence, Antimicrobial Resistance, and Plasmid Profiles ofMicrobial drug resistance (Larchmont, N.Y.) · 2019Article
- Determining antimicrobial susceptibility in Salmonella enterica serovar Typhimurium through whole genome sequencing: a comparison against multiple phenotypic susceptibility testing methods.BMC microbiology · 2019Article
- Present and Future Surveillance of Antimicrobial Resistance in Animals: Principles and Practices.Microbiology spectrum · 2018Review
- Review
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- Establishing Genotypic Cutoff Values To Measure Antimicrobial Resistance in Salmonella.Antimicrobial agents and chemotherapy · 2017Article
- Whole-Genome Sequencing for Detecting Antimicrobial Resistance in Nontyphoidal Salmonella.Antimicrobial agents and chemotherapy · 2016Article
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5 authors.
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Abstract
For Enterobacteriaceae such as Salmonella spp. and Escherichia coli, no unified interpretive resistance criteria exist for streptomycin, an epidemiologically important antibiotic. As part of the National Antimicrobial Resistance Monitoring System, we had previously used a minimum inhibitory concentration of ≥ 64 μg mL(-1) as an epidemiological cutoff value (ECV) to define non-wild-type isolates. To identify whether this ECV correlated with genetic determinants of resistance, we performed whole-genome sequencing of 463 Salmonella and E. coli isolates to identify streptomycin resistance genotypes. From this analysis, we found that using a streptomycin resistance breakpoint of ≥ 64 μg mL(-1) classified over 20% of strains possessing aadA or strA/strB resistance genes as wild-type. Therefore, to improve the concordance between genotypic and phenotypic data, we propose reducing the phenotypic cutoff values to ≥ 32 μg mL(-1) for both Salmonella and E. coli, to be used widely as ECVs to categorize non-wild-type isolates.
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