Plasma fetuin-A triggers inflammatory changes in macrophages and adipocytes by acting as an adaptor protein between NEFA and TLR-4.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 28 citations in OpenAlex.

1. Relationship ofCanadian journal of gastroenterology & hepatology · 2023
   Pooled it
2. Effects of exercise training on Fetuin-a in obese, type 2 diabetes and cardiovascular disease in adults and elderly: a systematic review and Meta-analysis.Lipids in health and disease · 2019
   Pooled it
3. Clinical and Biochemical Parameters in Relation to Serum Fetuin-A Levels in Overweight and Obese with and without Metabolic Syndrome in the North-eastern States of Indian Population.JMA journal · 2024
   Article
4. Transcriptional control of metabolism by interferon regulatory factors.Nature reviews. Endocrinology · 2024
   Review
5. Friend or foe for obesity: How hepatokines remodel adipose tissues and translational perspective.Genes & diseases · 2023
   Review
6. Interorgan communication with the liver: novel mechanisms and therapeutic targets.Frontiers in immunology · 2023
   Review
7. Fetuin-A is an immunomodulator and a potential therapeutic option in BMP4-dependent heterotopic ossification and associated bone mass loss.Bone research · 2022
   Article
8. Hepatokines and Non-Alcoholic Fatty Liver Disease: Linking Liver Pathophysiology to Metabolism.Biomedicines · 2021
   Review
9. Hepatokine Pregnancy Zone Protein Governs the Diet-Induced Thermogenesis Through Activating Brown Adipose Tissue.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2021
   Article
10. Detection and Characterization of Phosphorylation, Glycosylation, and Fatty Acid Bound to Fetuin A in Human Blood.Journal of clinical medicine · 2021
    Article
11. Fetuin-A is a HIF target that safeguards tissue integrity during hypoxic stress.Nature communications · 2021
    Article
12. Impact of Sarcopenia on the Severity of the Liver Damage in Patients With Non-alcoholic Fatty Liver Disease.Frontiers in nutrition · 2021
    Review
13. The Role of Exercise in the Interplay between Myokines, Hepatokines, Osteokines, Adipokines, and Modulation of Inflammation for Energy Substrate Redistribution and Fat Mass Loss: A Review.Nutrients · 2020
    Review
14. Inter-organ cross-talk in metabolic syndrome.Nature metabolism · 2019
    Review
15. Cytokines and Abnormal Glucose and Lipid Metabolism.Frontiers in endocrinology · 2019
    Review
16. Correlation analysis of monocyte subsets and insulin resistance considering fetuin-A involvement in patients with type 2 diabetes.Clinical and translational medicine · 2018
    Article
17. Does elevated bilirubin aid weight control by preventing development of hypothalamic leptin resistance?Open heart
    Article

Corrections and comments

• Comment on
  Plasma fetuin-A does not correlate with monocyte TLR4 in humans.2016

Authors and funding

2 authors at 1 institution in 1 country.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

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