ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2016
Impact of nine chronic conditions for US adults aged 65 years and older: an application of a hybrid estimator of quality-adjusted life years throughout remainder of lifetime.
Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- The impact of depression on mortality among older adult patients with hypertension: a systematic review and meta-analysis.Frontiers in public health · 2025Pooled it
- Pooled it
- Health-related quality of life and lifetime QALY loss among Indigenous Australians with chronic conditions: an age-stratified analysis.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026Article
- Cost-effectiveness analysis of a bone metastasis cancer board for skeletal-related events of breast cancer.Japanese journal of clinical oncology · 2026Article
- QALY losses for non-communicable diseases in Iranian adults: insights from a national cross-sectional study.Population health metrics · 2026Article
- Healthy life expectancy with cardiovascular disease among Chinese rural population based on the prospective cohort study.Journal of geriatric cardiology : JGC · 2024Article
- Sexual Functioning and Sexual Health in Female Patients following Stroke: A Scoping Review with Implications for Rehabilitation.Journal of personalized medicine · 2024Article
- Socioeconomic Disparities in Individual-Level Quality-Adjusted Life Years throughout Remaining Lifetimes: A National Representative Longitudinal Survey in China.International journal of environmental research and public health · 2023Article
- Article
- QALY losses for chronic diseases and its social distribution in the general population: results from the Belgian Health Interview Survey.BMC public health · 2022Article
- The impact of multimorbidity patterns on health-related quality of life in the general population: results of the Belgian Health Interview Survey.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2022Article
- Developing the Total Health Profile, a Generalizable Unified Set of Multimorbidity Risk Scores Derived From Machine Learning for Broad Patient Populations: Retrospective Cohort Study.Journal of medical Internet research · 2021Article
- Relationship between Quality of Life and Sociodemographic, Physical and Mental Health Variables in People over 65 in the Community of Madrid.International journal of environmental research and public health · 2020Article
- Cost-Effectiveness Analysis of Four Common Diagnostic Methods for Clostridioides difficile Infection.Journal of general internal medicine · 2020Article
- Emergency department and inpatient utilization among U.S. older adults with multiple chronic conditions: a post-reform update.BMC health services research · 2020Article
- Burden of disease associated with lower levels of income among US adults aged 65 and older.BMJ open · 2017Article
- Incremental decreases in quality-adjusted life years (QALY) associated with higher levels of depressive symptoms for U.S. Adults aged 65 years and older.Health and quality of life outcomes · 2017Article
- An Official American Thoracic Society Workshop Report: Evaluation and Management of Asthma in the Elderly.Annals of the American Thoracic Society · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo estimate quality-adjusted life years (QALY) loss due to each of the following nine chronic conditions-depression, diabetes mellitus, hypertension, heart disease, stroke, emphysema, asthma, arthritis, and cancer.
methodsWe ascertained respondents' health-related quality of life scores and mortality status from the 2005 to 2008 National Health and Nutrition Examination Survey (NHANES) with mortality follow-up data through December 31, 2011. We included respondents aged 65 years and older (n = 2380). A hybrid estimator was used to calculate QALY from two parts: QALY during the follow-up period and QALY beyond the follow-up period. We calculated QALY by each of the nine chronic conditions.
resultsFor persons aged 65 and older, QALY throughout the reminder of lifetime was 12.3 years. After adjusting for age- and sex-related differences, depression had an associated 8.2 years of QALY loss; diabetes, 5.6 years; hypertension, 2.5 years; heart disease, 5.4 years; stroke, 6.4 years; emphysema, 8.0 years; asthma, 4.8 years; arthritis, 0.3 years; and cancer, 2.5 years. Compared to persons without any chronic conditions, persons with one condition had an associated 4.7 years of QALY loss; persons with two conditions, 7.9 years; and persons with three or more conditions, 10.8 years.
conclusionsThis study presents a QALY estimator for respondents in the NHANES-Linked Mortality File and demonstrates the utility of this method to other follow-up data. Continued application of our method would enable the burden of disease to be compared for a range of health conditions and risk factors in the ongoing effort to improve population health.
Indexed as
Identifiers
26781442What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.