Evidence map›Paper›PMID 26781090›Full record

ArticleHuman genetics2016

Resolving the ancestry of Austronesian-speaking populations.

Pedro A Soares, Jean A Trejaut, Teresa Rito, Bruno Cavadas, Catherine Hill, Ken Khong Eng, Maru Mormina, Andreia Brandão, Ross M Fraser, Tse-Yi Wang and 13 more

Abstract read
In one paragraph

Article in Human genetics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed.

  1. Article
  2. Review
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  4. Article
  5. Article
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  11. Mitogenomics of modern Mongolic-speaking populations.Molecular genetics and genomics : MGG · 2022
    Article
  12. Review
  13. Article
  14. Multiple migrations to the Philippines during the last 50,000 years.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  15. Article
  16. Article
  17. The paternal and maternal genetic history of Vietnamese populations.European journal of human genetics : EJHG · 2020
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

Pedro A SoaresDepartment of Biology, CBMA (Centre of Molecular and Environmental Biology), University of Minho, Campus de Gualtar, 4710-057, Braga, Portugal.
Jean A TrejautMolecular Anthropology and Transfusion Medicine Research Laboratory, Mackay Memorial Hospital, Taipei City, 10449, Taiwan.
Teresa RitoIPATIMUP (Institute of Molecular Pathology and Immunology of the University of Porto), Rua Dr. Roberto Frias s/n, 4200-465, Porto, Portugal.
Bruno CavadasIPATIMUP (Institute of Molecular Pathology and Immunology of the University of Porto), Rua Dr. Roberto Frias s/n, 4200-465, Porto, Portugal.
Catherine HillFaculty of Biological Sciences, University of Leeds, Leeds, LS2 9JT, UK.
Ken Khong EngFaculty of Biological Sciences, University of Leeds, Leeds, LS2 9JT, UK.
Maru MorminaFaculty of Biological Sciences, University of Leeds, Leeds, LS2 9JT, UK.
Andreia BrandãoIPATIMUP (Institute of Molecular Pathology and Immunology of the University of Porto), Rua Dr. Roberto Frias s/n, 4200-465, Porto, Portugal.
Ross M FraserCentre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Teviot Place, Edinburgh, EH8 9AG, Scotland, UK.
Tse-Yi WangMolecular Anthropology and Transfusion Medicine Research Laboratory, Mackay Memorial Hospital, Taipei City, 10449, Taiwan.
Jun-Hun LooMolecular Anthropology and Transfusion Medicine Research Laboratory, Mackay Memorial Hospital, Taipei City, 10449, Taiwan.
Christopher SnellFaculty of Biological Sciences, University of Leeds, Leeds, LS2 9JT, UK.
Tsang-Ming KoDepartment of Obstetrics and Gynecology, National Taiwan University, Roosevelt Rd., Taipei, 10617, Taiwan.
António AmorimIPATIMUP (Institute of Molecular Pathology and Immunology of the University of Porto), Rua Dr. Roberto Frias s/n, 4200-465, Porto, Portugal.
Maria PalaDepartment of Biological Sciences, School of Applied Sciences, University of Huddersfield, Queensgate, Huddersfield, HD1 3DH, UK.
Vincent MacaulayDepartment of Statistics, University of Glasgow, 15 University Gardens, Glasgow, G12 8QQ, UK.
David BulbeckDepartment of Archaeology and Natural History, College of Asia and the Pacific, The Australian National University, Acton, Canberra, ACT, 2601, Australia.
James F WilsonCentre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Teviot Place, Edinburgh, EH8 9AG, Scotland, UK.
Leonor GusmãoIPATIMUP (Institute of Molecular Pathology and Immunology of the University of Porto), Rua Dr. Roberto Frias s/n, 4200-465, Porto, Portugal.
Luísa PereiraIPATIMUP (Institute of Molecular Pathology and Immunology of the University of Porto), Rua Dr. Roberto Frias s/n, 4200-465, Porto, Portugal.
Stephen OppenheimerInstitute of Human Sciences, School of Anthropology, University of Oxford, The Pauling Centre, 58a Banbury Road, Oxford, OX2 6QS, UK.
Marie LinMolecular Anthropology and Transfusion Medicine Research Laboratory, Mackay Memorial Hospital, Taipei City, 10449, Taiwan.
Martin B RichardsFaculty of Biological Sciences, University of Leeds, Leeds, LS2 9JT, UK. m.b.richards@hud.ac.uk.

Funding

Medical Research Council MC_PC_U127561128
6 · The paper itself

Abstract

There are two very different interpretations of the prehistory of Island Southeast Asia (ISEA), with genetic evidence invoked in support of both. The "out-of-Taiwan" model proposes a major Late Holocene expansion of Neolithic Austronesian speakers from Taiwan. An alternative, proposing that Late Glacial/postglacial sea-level rises triggered largely autochthonous dispersals, accounts for some otherwise enigmatic genetic patterns, but fails to explain the Austronesian language dispersal. Combining mitochondrial DNA (mtDNA), Y-chromosome and genome-wide data, we performed the most comprehensive analysis of the region to date, obtaining highly consistent results across all three systems and allowing us to reconcile the models. We infer a primarily common ancestry for Taiwan/ISEA populations established before the Neolithic, but also detected clear signals of two minor Late Holocene migrations, probably representing Neolithic input from both Mainland Southeast Asia and South China, via Taiwan. This latter may therefore have mediated the Austronesian language dispersal, implying small-scale migration and language shift rather than large-scale expansion.

Indexed as

Genome, HumanAsian PeopleAsia, SoutheasternChromosomes, Human, YDatabases, GeneticDNA, MitochondrialFemaleGenetic Association StudiesGenetic LociHumansMaleModels, GeneticPhylogenyPhylogeographyPolymorphism, Single NucleotideReproducibility of ResultsDNA, Mitochondrial

Identifiers

PMID26781090
PMCPMC4757630

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.