ArticleeLife2016
The cerebellum linearly encodes whisker position during voluntary movement.
Article in eLife, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
57 citing papers in PubMed.
- Representations of Subsecond Duration-Based Timing by Complex Spike Synchrony in Cerebellar Purkinje Neurons.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Effects of Short-Term Synaptic Plasticity in Feedforward Inhibitory Circuits on Cerebellar Responses to Repetitive Sensory Input.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Temporal dynamics between the whisker sensorimotor cortex and the olivocerebellar module in awake mice.Frontiers in cellular neuroscience · 2026Article
- Stage-dependent cerebrocerebellar communication during sensorimotor processing.Nature communications · 2025Article
- High-speed voltage imaging of action potentials in molecular layer interneurons reveals sensory-driven synchrony that augments movement.Cell reports · 2025Article
- Article
- Cerebellar control of targeted tongue movements.The Journal of physiology · 2025Article
- The cerebellum converts input data into a hyper low-resolution granule cell code with spatial dimensions: a hypothesis.Royal Society open science · 2025Article
- GlyT2-Positive Interneurons Regulate Timing and Variability of Information Transfer in a Cerebellar-Behavioral Loop.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- The cerebellum engages multiple pre-motor pathways through a divergent-convergent architecture to shape whisker dynamics.Frontiers in neural circuits · 2025Article
- Article
- Local synaptic inhibition mediates cerebellar granule cell pattern separation and enables learned sensorimotor associations.Nature neuroscience · 2024Article
- Cerebellar state estimation enables resilient coupling across behavioural domains.Scientific reports · 2024Article
- Interchangeable Role of Motor Cortex and Reafference for the Stable Execution of an Orofacial Action.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- What Can We Learn from Synaptic Connectivity Maps about Cerebellar Internal Models?Cerebellum (London, England) · 2023Review
- Cerebellar contributions across behavioural timescales: a review from the perspective of cerebro-cerebellar interactions.Frontiers in systems neuroscience · 2023Review
- The Shape of Data: a Theory of the Representation of Information in the Cerebellar Cortex.Cerebellum (London, England) · 2022Article
- Impact of Purkinje Cell Simple Spike Synchrony on Signal Transmission from Flocculus.Cerebellum (London, England) · 2022Article
- Purkinje Cell Activity Resonation Generates Rhythmic Behaviors at the Preferred Frequency of 8 Hz.Biomedicines · 2022Article
- The Cerebellar Cortex.Annual review of neuroscience · 2022Review
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
Active whisking is an important model sensorimotor behavior, but the function of the cerebellum in the rodent whisker system is unknown. We have made patch clamp recordings from Purkinje cells in vivo to identify whether cerebellar output encodes kinematic features of whisking including the phase and set point. We show that Purkinje cell spiking activity changes strongly during whisking bouts. On average, the changes in simple spike rate coincide with or slightly precede movement, indicating that the synaptic drive responsible for these changes is predominantly of efferent (motor) rather than re-afferent (sensory) origin. Remarkably, on-going changes in simple spike rate provide an accurate linear read-out of whisker set point. Thus, despite receiving several hundred thousand discrete synaptic inputs across a non-linear dendritic tree, Purkinje cells integrate parallel fiber input to generate precise information about whisking kinematics through linear changes in firing rate.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.