Evidence map›Paper›PMID 26780746›Full record

ReviewJournal of thrombosis and thrombolysis2016

Guidance for the practical management of warfarin therapy in the treatment of venous thromboembolism.

Daniel M Witt, Nathan P Clark, Scott Kaatz, Terri Schnurr, Jack E Ansell

Open access · hybridAbstract readReview
In one paragraph

Review in Journal of thrombosis and thrombolysis, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
65citing papers in PubMed, 5 pooled it
11.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

65 citing papers in PubMed, 5 syntheses or guidelines pooled it, 150 citations in OpenAlex.

  1. Guideline
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Article
  7. Article
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  9. Review
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  11. Article
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  16. Review
  17. Article
  18. Article
  19. Psychological Impact of Pulmonary Embolism: A Narrative Review.Journal of community hospital internal medicine perspectives · 2025
    Review
  20. Article

5 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 5 institutions in 2 countries.

Daniel M WittUniversity of Utah College of Pharmacy, 30 South 2000 East, Salt Lake City, UT, 84112, USA. dan.witt@pharm.utah.edu.
Nathan P ClarkClinical Pharmacy Anticoagulation and Anemia Services, Kaiser Permanente Colorado, University of Colorado Skaggs School of Pharmacy and Pharmaceutical Services, Aurora, CO, USA.
Scott KaatzHurley Medical Center, Flint, MI, USA.
Terri SchnurrThromboembolism Research and Thoracic Surgery Research, St. Joseph's Healthcare, Hamilton, ON, Canada.
Jack E AnsellHofstra North Shore/LIJ School of Medicine, Hempstead, NY, USA.
Hofstra University · USKaiser Permanente · USMichigan State University · USSt. Joseph’s Healthcare Hamilton · CAUniversity of Utah · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Venous thromboembolism (VTE) is a serious and often fatal medical condition with an increasing incidence. The treatment of VTE is undergoing tremendous changes with the introduction of the new direct oral anticoagulants and clinicians need to understand new treatment paradigms. This article, initiated by the Anticoagulation Forum, provides clinical guidance based on existing guidelines and consensus expert opinion where guidelines are lacking. Well-managed warfarin therapy remains an important anticoagulant option and it is hoped that anticoagulation providers will find the guidance contained in this article increases their ability to achieve optimal outcomes for their patients with VTE Pivotal practical questions pertaining to this topic were developed by consensus of the authors and were derived from evidence-based consensus statements whenever possible. The medical literature was reviewed and summarized using guidance statements that reflect the consensus opinion(s) of all authors and the endorsement of the Anticoagulation Forum's Board of Directors. In an effort to provide practical and implementable information about VTE and its treatment, guidance statements pertaining to choosing good candidates for warfarin therapy, warfarin initiation, optimizing warfarin control, invasive procedure management, excessive anticoagulation, subtherapeutic anticoagulation, drug interactions, switching between anticoagulants, and care transitions are provided.

Indexed as

HumansPractice Guidelines as TopicVenous ThromboembolismWarfarinWarfarinAnticoagulationAnticoagulation clinicsAnticoagulation-related bleedingCoumadinDirect oral anticoagulants (DOAC)Drug interactionsINRRisk factorsVenous thromboembolismWarfarin

Identifiers

PMID26780746
PMCPMC4715850
OpenAlexW2330467346

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.