ReviewJournal of thrombosis and thrombolysis2016
Guidance for the evaluation and treatment of hereditary and acquired thrombophilia.
Review in Journal of thrombosis and thrombolysis, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 117 papers.
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Who cites it
117 citing papers in PubMed, 333 citations in OpenAlex.
- Anticoagulant protein activity value thresholds for the occurrence of venous thromboembolism in pregnant women with thrombophilia.International journal of hematology · 2026Article
- Beyond the Thrombophilia Panel: Real-World Overuse, Limited Interpretability, and Poor Guideline Concordance in a Hematology Referral Cohort.Diagnostics (Basel, Switzerland) · 2026Article
- Risks of anticoagulation discontinuation after first venous thromboembolism in inherited thrombophilia: a long-term cohort study.Research and practice in thrombosis and haemostasis · 2026Article
- A scoring system to predict life-threatening thromboischemic events in patients with acute promyelocytic leukemia: the PETHEMA/PALG study.Haematologica · 2026Article
- Impact of coagulation disorders on intracranial hemorrhage outcomes: a case-controlled study.Neurosurgical review · 2025Article
- Review
- Analysis of Treatment and Subsequent Pregnancy Outcomes in Patients With Antinuclear Antibody-Positive Recurrent Spontaneous Abortion.Immunity, inflammation and disease · 2025Article
- Etiology and Risk Factors for Splanchnic Vein Thrombosis in Non-Cirrhotic, Non-Neoplastic Patients: A Narrative Review.Medicina (Kaunas, Lithuania) · 2025Review
- Systemic thrombosis with prothrombin Belgrade mutation in a Chinese patient: A case report.World journal of clinical cases · 2025Article
- Article
- The novel SERPINC1 missense mutation c.1148 T > A (p.L383H) causes hereditary antithrombin deficiency and thromboembolism in a Chinese family: a case report.Journal of medical case reports · 2025Article
- Prevalence and factors associated with high-risk thrombophilia: a single-center cross-sectional study of 3550 patients at a tertiary Thrombosis Centre in Switzerland.Research and practice in thrombosis and haemostasis · 2025Article
- [Endovascular treatment of chronic pelvic vein obstruction].Innere Medizin (Heidelberg, Germany) · 2025Review
- Opium Addiction and Coagulation Factors in ST-Segment Elevation Myocardial Infarction (STEMI) Patients: Implications for Thrombosis and Cardiovascular Outcomes.Iranian journal of public health · 2025Article
- The Relationship Between Thrombophilia and Modifications in First-Trimester Prenatal Screening Markers.Medicina (Kaunas, Lithuania) · 2025Observational
- A Serious Headache: Lessons Learned from the Management of Pregnancy-Associated Venous Sinus Thrombosis in a Region with Limited Abortion Access.Neurocritical care · 2025Article
- Prevalence of antiphospholipid syndrome among women with recurrent pregnancy loss: a cohort study.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2025Article
- Venous Thromboembolism: Current Insights and Future Directions.The International journal of angiology : official publication of the International College of Angiology, Inc · 2024Review
- Article
- Clinical characteristics and thrombophilia associated gene variants in Egyptians with unprovoked venous thromboembolism: three centers experience.Molecular biology reports · 2024Article
57 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
8 authors at 6 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Thrombophilias are hereditary and/or acquired conditions that predispose patients to thrombosis. Testing for thrombophilia is commonly performed in patients with venous thrombosis and their relatives; however such testing usually does not provide information that impacts management and may result in harm. This manuscript, initiated by the Anticoagulation Forum, provides clinical guidance for thrombophilia testing in five clinical situations: following 1) provoked venous thromboembolism, 2) unprovoked venous thromboembolism; 3) in relatives of patients with thrombosis, 4) in female relatives of patients with thrombosis considering estrogen use; and 5) in female relatives of patients with thrombosis who are considering pregnancy. Additionally, guidance is provided regarding the timing of thrombophilia testing. The role of thrombophilia testing in arterial thrombosis and for evaluation of recurrent pregnancy loss is not addressed. Statements are based on existing guidelines and consensus expert opinion where guidelines are lacking. We recommend that thrombophilia testing not be performed in most situations. When performed, it should be used in a highly selective manner, and only in circumstances where the information obtained will influence a decision important to the patient, and outweigh the potential risks of testing. Testing should not be performed during acute thrombosis or during the initial (3-month) period of anticoagulation.
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