Evidence map›Paper›PMID 26780581›Full record

SynthesisClinical psychology review2016

Attention-deficit/hyperactivity disorder (ADHD) and being overweight/obesity: New data and meta-analysis.

Joel T Nigg, Jeanette M Johnstone, Erica D Musser, Hilary Galloway Long, Michael T Willoughby, Jackilen Shannon

Registry-linked trialAbstract readMeta-AnalysisReview
In one paragraph

Synthesis in Clinical psychology review, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04601779 (INFANT HEALTH- Supporting Infants' Mental Health and Healthy Weight Development Through Community Health Nurses' Promoting Sensitive Parenting), which is not on this map. Cited by 93 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
93citing papers in PubMed, 4 pooled it
7.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04601779 nacompletednot on this mapstarted 2021, after this paper: background citation

INFANT HEALTH- Supporting Infants' Mental Health and Healthy Weight Development Through Community Health Nurses' Promoting Sensitive Parenting

TypeinterventionalSponsorUniversity of Southern DenmarkRan2021 to 2025Enrolled406ConditionsInfant Mental Health, Parenting, Parent-Child RelationsArmsVIPP-PUF
3 · Its place in the literature

Who cites it

93 citing papers in PubMed, 4 syntheses or guidelines pooled it, 205 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Review
  6. ADHD and metabolic syndrome: behavioral and weight-related pathways to cardiovascular risk.European archives of psychiatry and clinical neuroscience · 2026
    Article
  7. Physical Fitness Profiles Among Children and Adolescents With ADHD and ASD: A Comparison With Typically Developing Peers.Autism research : official journal of the International Society for Autism Research · 2026
    Article
  8. Review
  9. Article
  10. Attention-deficit/hyperactivity disorder (ADHD) in adults: evidence base, uncertainties and controversies.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2025
    Article
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33 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Joel T NiggOregon Health & Science University, Portland, OR, United States. Electronic address: niggj@ohsu.edu.
Jeanette M JohnstoneOregon Health & Science University, Portland, OR, United States.
Erica D MusserFlorida International University, Miami, FL, United States.
Hilary Galloway LongOregon Health & Science University, Portland, OR, United States.
Michael T WilloughbyRTI International, Research Triangle Park, NC, United States.
Jackilen ShannonOregon Health & Science University, Portland, OR, United States.
Oregon Health & Science University · USFlorida International University · USRTI International · US

Funding

CAM Research Training in Neuroscience &StressT32AT002688 · NCCIH · OREGON HEALTH & SCIENCE UNIVERSITY · PI OKEN, BARRY S, SOUMYANATH, AMALA · 2005 to 2025
$7.2M
ADHD heterogeneity, mechanisms, and risk profileR37MH059105 · NIMH · OREGON HEALTH & SCIENCE UNIVERSITY · PI NIGG, JOEL T · 2014 to 2023
$7.0M
Brain trajectories in ADHDR01MH115357 · NIMH · OREGON HEALTH & SCIENCE UNIVERSITY · PI FAIR, DAMIEN A, NIGG, JOEL T · 2017 to 2021
$3.8M
NEUROPSYCHOLOGICAL AND FAMILIAL MARKERS FOR CHILD ADHDR01MH059105 · NIMH · OREGON HEALTH & SCIENCE UNIVERSITY · PI NIGG, JOEL T · 1999 to 2012
$3.3M
NCCIH NIH HHS T32 AT002688NIMH NIH HHS R01 MH059105NIMH NIH HHS R01 MH115357NIMH NIH HHS R37 MH059105NIMH NIH HHS R37-MH59105
6 · The paper itself

Abstract

backgroundLiterature has suggested that ADHD may be associated with increased risk of obesity. If so, this would have important clinical implications.

objectiveTo clarify the size of the association between ADHD and obesity and to evaluate key moderators of the association including medication, gender, age, and psychiatric comorbidity.

methodTwo preliminary studies are presented to supply critical additional data for the meta-analysis: a two-year longitudinal study of an ADHD case-control sample of 313 children aged 7-11, and a national survey study of 45,309 families in the United States using the 2012 National Survey of Children's Health. Formal meta-analysis was then conducted. The identification procedure yielded 43 studies, reporting 225 comparisons or effect sizes, studying 703,937 participants An overall effect size was estimated with a random effects model (after pooling within study using a modified fixed effects model). Effect size was then examined in relation to medication, gender, age, and psychiatric comorbidity.

resultsThe new study of children revealed no reliable association of ADHD and body mass index at any age or time point. In the national survey, ADHD was associated with obesity only in adolescent girls but not in children or boys; this effect was statistically accounted for by covarying of depression and conduct disorder. In the meta-analysis, the composite effect size was OR=1.22 (95% CI=1.11-1.34); 22 studies provided effects with medication controlled, yielding a composite effect size of OR=1.30 (95% CI=1.12-1.50). Pooled across age the association without covariates was reliable in females (OR=1.19 [1.01-1.41]) but not males (OR=1.10 [0.95-1.23]) although males and females did not statistically differ. Pooled across gender, the association was significantly larger in adults (>18years) (OR=1.37 [1.19-1.58]) than in youth (OR=1.13 [1.00-1.27]), p=.04.

conclusionsADHD has a small overall association with obesity, but this effect is moderate in adults. The effect is likely to be of no clinical significance in children, possible clinical significance in adolescent girls with comorbid disorders, and of clinical relevance by adulthood.

Indexed as

ComorbidityAdolescentAttention Deficit Disorder with HyperactivityChildFemaleHumansMaleOverweightADHDAttentionBody mass indexImpulsivityObesityOverweight

Identifiers

PMID26780581
PMCPMC4800333
OpenAlexW2184012263

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.