Evidence map›Paper›PMID 26780528›Full record

ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2017

Value of attenuation correction in stress-only myocardial perfusion imaging using CZT-SPECT.

J D van Dijk, M Mouden, J P Ottervanger, J A van Dalen, S Knollema, C H Slump, P L Jager

Open access · hybridAbstract readComparative StudyEvaluation Study
In one paragraph

Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
4.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 51 citations in OpenAlex.

  1. Trial
  2. Article
  3. Deep learning-based obstructive coronary artery disease prediction from myocardial perfusion SPECT.European journal of nuclear medicine and molecular imaging · 2026
    Article
  4. Article
  5. Article
  6. CT attenuation correction improves quantitative risk prediction by cardiac SPECT in obese patients.European journal of nuclear medicine and molecular imaging · 2024
    Article
  7. Article
  8. Article
  9. Deep Learning-Based Attenuation Correction Improves Diagnostic Accuracy of Cardiac SPECT.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2023
    Article
  10. Article
  11. Article
  12. Deep learning, another important tool for improving acquisition efficiency in SPECT MPI Imaging.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021
    Article
  13. Review
  14. Visually estimated coronary artery calcium score improves SPECT-MPI risk stratification.International journal of cardiology. Heart & vasculature · 2021
    Article
  15. Quantitative analysis: Specific normal database for the best practice.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021
    Article
  16. Deep learning-based attenuation map generation for myocardial perfusion SPECT.European journal of nuclear medicine and molecular imaging · 2020
    Article
  17. Myocardial perfusion imaging in overweight patients and women: Is it CZT good enough?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2020
    Article
  18. Rationale and design of the REgistry of Fast Myocardial Perfusion Imaging with NExt generation SPECT (REFINE SPECT).Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2020
    Article
  19. Improved diagnostic accuracy of thallium-201 myocardial perfusion single-photon emission computed tomography with CT attenuation correction.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2019
    Article
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

J D van DijkDepartment of Nuclear Medicine, Isala Hospital, PO Box 10400, 8000 GK, Zwolle, The Netherlands. jorisvdijk@gmail.com.
M MoudenDepartment of Cardiology, Isala Hospital, Zwolle, The Netherlands.
J P OttervangerDepartment of Cardiology, Isala Hospital, Zwolle, The Netherlands.
J A van DalenDepartment of Medical Physics, Isala Hospital, Zwolle, The Netherlands.
S KnollemaDepartment of Nuclear Medicine, Isala Hospital, PO Box 10400, 8000 GK, Zwolle, The Netherlands.
C H SlumpMIRA: Institute for Biomedical Technology and Technical Medicine, University of Twente, Enschede, The Netherlands.
P L JagerDepartment of Nuclear Medicine, Isala Hospital, PO Box 10400, 8000 GK, Zwolle, The Netherlands.
Isala · NLUniversity of Twente · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAttenuation correction (AC) improves the diagnostic outcome of stress-only myocardial perfusion imaging (MPI) using conventional SPECT. Our aim was to determine the value of AC using a cadmium zinc telluride-based (CZT)-SPECT camera. METHODS AND

resultsWe retrospectively included 107 consecutive patients who underwent stress-optional rest MPI CZT-SPECT/CT. Next, we created three types of images for each patient; (1) only displaying reconstructed data without the CT-based AC (NC), (2) only displaying AC, and (3) with both NC and AC (NC + AC). Next, two experienced physicians visually interpreted these 321 randomized images as normal, equivocal, or abnormal. Image outcome was compared with all hard events over a mean follow-up time of 47.7 ± 9.8 months. The percentage of images interpreted as normal increased from 45% using the NC images to 72% using AC and to 67% using NC + AC images (P < .001). Hard event hazard ratios for images interpreted as normal were not different between using NC and AC (1.01, P = .99), or NC and NC + AC images (0.97, P = .97).

conclusionsAC lowers the need for additional rest imaging in stress-first MPI using CZT-SPECT, while long-term patient outcome remained identical. Use of AC reduces the need for additional rest imaging, decreasing the mean effective dose by up to 1.2 mSv.

Indexed as

ArtifactsAlgorithmsCadmiumEquipment DesignEquipment Failure AnalysisExercise TestHumansImage EnhancementMiddle AgedMyocardial IschemiaMyocardial Perfusion ImagingNetherlandsObserver VariationPrevalencePrognosisRadionuclide ImagingCadmiumCdZnTeTelluriumZincAttenuation correctionCdZnTemyocardial perfusion imaging: SPECTstress-only

Identifiers

PMID26780528
PMCPMC5413515
OpenAlexW2289385243

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.