ArticleInvestigative ophthalmology & visual science2016
Nonhuman Primate Ocular Biometry.
Article in Investigative ophthalmology & visual science, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
14 citing papers in PubMed, 26 citations in OpenAlex.
- Aging of Nonhuman Primate Eyes Is Sexually Dimorphic.Investigative ophthalmology & visual science · 2026Article
- Article
- Model of zonular forces on the lens capsule during accommodation.Scientific reports · 2024Article
- Animal Models in Eye Research: Focus on Corneal Pathologies.International journal of molecular sciences · 2023Review
- Nonhuman Primate Eyes Display Variable Growth and Aging Rates in Alignment With Human Eyes.Investigative ophthalmology & visual science · 2023Article
- Inhibitory effect of lanosterol on cataractous lens of cynomolgus monkeys using a subconjunctival drug release system.Precision clinical medicine · 2022Article
- Comparing low-coherence interferometry and A-scan ultrasonography in measuring ocular axial dimensions in young rhesus monkeys.Experimental eye research · 2022Article
- Normative Data of Ocular Biometry, Optical Coherence Tomography, and Electrophysiology Conducted for Cynomolgus Macaque Monkeys.Translational vision science & technology · 2021Article
- The Emerging Role of Topical Ocular Drugs to Target the Posterior Eye.Ophthalmology and therapy · 2021Review
- The Relationship Between Macula Retinal Ganglion Cell Density and Visual Function in the Nonhuman Primate.Investigative ophthalmology & visual science · 2021Article
- Tissue Responses and Wound Healing following Laser Scleral Microporation for Presbyopia Therapy.Translational vision science & technology · 2020Article
- A parameterized digital 3D model of the Rhesus macaque face for investigating the visual processing of social cues.Journal of neuroscience methods · 2019Article
- Higher-Order-Aberrations Following Hyperopia Treatment: Small Incision Lenticule Extraction, Laser-Assisted In Situ Keratomileusis and Lenticule Implantation.Translational vision science & technology · 2018Article
- Peripheral Defocus of the Monkey Crystalline Lens With Accommodation in a Lens Stretcher.Investigative ophthalmology & visual science · 2018Article
Corrections and comments
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Authors and funding
4 authors at 4 institutions in 2 countries.
Funding
Abstract
purposeTo examine ocular growth in nonhuman primates (NHPs) from measurements on ex vivo eyes.
methodsWe obtained NHP eyes from animals that had been killed as part of other studies or because of health-related issues. Digital calipers were used to measure the horizontal, vertical, and anteroposterior globe diameters as well as corneal horizontal and vertical diameters of excised globes from 98 hamadryas baboons, 551 cynomolgus monkeys, and 112 rhesus monkeys, at ages ranging from 23 to 360 months. Isolated lens sagittal thickness and equatorial diameter were measured by shadowphotogrammetry. Wet and fixed dry weights were obtained for lenses.
resultsNonhuman primate globe growth continues throughout life, slowing toward an asymptotic maximum. The final globe size scales with negative allometry to adult body size. Corneal growth ceases at around 20 months. Lens diameter increases but thickness decreases with increasing age. Nonhuman primate lens wet and dry weight accumulation is monophasic, continuing throughout life toward asymptotic maxima. The dry/wet weight ratio reaches a maximum of 0.33.
conclusionsNonhuman primate ocular globe and lens growth differ in several respects from those in humans. Although age-related losses of lens power and accommodative amplitude are similar, lens growth and properties are different indicating care should be taken in extrapolating NHP observations to the study of human accommodation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.