ArticleFrontiers in plant science2015
Evidence that KARRIKIN-INSENSITIVE2 (KAI2) Receptors may Perceive an Unknown Signal that is not Karrikin or Strigolactone.
Article in Frontiers in plant science, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 88 papers.
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Who cites it
88 citing papers in PubMed, 169 citations in OpenAlex.
- From smoke to symbiosis: dissecting KAI2 signaling in rice using the specific receptor agonist, dMGer.Plant physiology · 2026Article
- Negative feedback regulation of karrikin signaling inProceedings of the National Academy of Sciences of the United States of America · 2026Article
- Orobanche cumana KAI2d2 mediates the perception of dehydrocostus lactone and strigolactones and is inhibited by triazole ureas.Plant communications · 2026Article
- Structural and functional characterisation of a reconstructed ancestral strigolactone receptor.The Plant journal : for cell and molecular biology · 2026Article
- Genomic and functional characterization of Rhizobium metallidurans NS41, a heavy-metal-resistant, non-legume-associated endophyte that reduces oxidative stress in metal-exposed maize.Molecular genetics and genomics : MGG · 2026Article
- Potent and Receptor-Selective Germination Inhibitor forPrecision chemistry · 2026Article
- Molecular insights into volatile organic compound sensing and signaling in plants.The Plant journal : for cell and molecular biology · 2026Review
- Overexpression of DWARF14-LIKE2 in Arabidopsis thaliana alters multiple traits related to plant morphology and osmotic and salt stress tolerance.Plant cell reports · 2026Article
- FveDAD2 negatively regulates branch crowns by affecting abscisic acid metabolism through FveHB7 in woodland strawberry.Horticulture research · 2026Article
- Crosstalk between strigolactone and KAI2/KL signalling in plant growth and stress responses.Frontiers in plant science · 2026Review
- An N-terminal domain specifies developmental control by the SMAX1-LIKE family of transcriptional regulators inProceedings of the National Academy of Sciences of the United States of America · 2025Article
- The Multifaceted Impact of Karrikin Signaling in Plants.International journal of molecular sciences · 2025Review
- Structural requirements of KAI2 ligands for activation of signal transduction.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- KAI2-dependent signaling controls vegetative reproduction in Marchantia polymorpha through activation of LOG-mediated cytokinin synthesis (14).Nature communications · 2025Article
- Identification and structure-guided development of triazole urea-based selective antagonists of Arabidopsis karrikin signaling.Nature communications · 2025Article
- HTL/KAI2 signaling substitutes for light to control plant germination.PLoS genetics · 2024Article
- SUPPRESSOR OF MAX2 1-LIKE (SMXL) homologs are MAX2-dependent repressors of Physcomitrium patens growth.The Plant cell · 2024Article
- Karrikin signalling: impacts on plant development and abiotic stress tolerance.Journal of experimental botany · 2024Article
- Molecular and Systems Biology Approaches for Harnessing the Symbiotic Interaction in Mycorrhizal Symbiosis for Grain and Oil Crop Cultivation.International journal of molecular sciences · 2024Review
- A Divergent Clade KAI2 Protein in the Root Parasitic Plant Orobanche minor Is a Highly Sensitive Strigolactone Receptor and Is Involved in the Perception of Sesquiterpene Lactones.Plant & cell physiology · 2023Article
28 more citing papers are in PubMed but not listed here.
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2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The α/β-hydrolases KAI2 and D14 are paralogous receptors for karrikins and strigolactones, two classes of plant growth regulators with butenolide moieties. KAI2 and D14 act in parallel signaling pathways that share a requirement for the F-box protein MAX2, but produce distinct growth responses by regulating different members of the SMAX1-LIKE/D53 family. kai2 and max2 mutants share seed germination, seedling growth, leaf shape, and petiole orientation phenotypes that are not found in d14 or SL-deficient mutants. This implies that KAI2 recognizes an unknown, endogenous signal, herein termed KAI2 ligand (KL). Recent studies of ligand-specificity among KAI2 paralogs in basal land plants and root parasitic plants suggest that karrikin and strigolactone perception may be evolutionary adaptations of KL receptors. Here we demonstrate that evolutionarily conserved KAI2c genes from two parasite species rescue multiple phenotypes of the Arabidopsis kai2 mutant, unlike karrikin-, and strigolactone-specific KAI2 paralogs. We hypothesize that KAI2c proteins recognize KL, which could be an undiscovered hormone.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.