ArticleFrontiers in microbiology2015
Microbiota Plays a Role in Oral Immune Priming in Tribolium castaneum.
Article in Frontiers in microbiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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Who cites it
31 citing papers in PubMed.
- Immune priming reshapes the microbiota and modulates pathogen dynamics in the Manila clam (Frontiers in microbiology · 2026Article
- Review
- Resources Modulate Developmental Shifts but Not Infection Tolerance Upon Co-Infection in an Insect System.Molecular ecology · 2025Article
- Immune priming in the insect gut: a dynamic response revealed by ultrastructural and transcriptomic changes.BMC biology · 2025Article
- Current insights into insect immune memory.eLife · 2025Review
- Dissecting transmission to understand parasite evolution.PLoS pathogens · 2025Review
- A taste of one's own medicine:Frontiers in immunology · 2025Article
- The gut microbiota confers resistance againstiScience · 2024Article
- Differential proteome profiling of bacterial culture supernatants reveals candidates for the induction of oral immune priming in the red flour beetle.Biology letters · 2023Article
- Anatomical study of the red flour beetle using synchrotron radiation X-ray phase-contrast micro-tomography.Journal of anatomy · 2023Review
- Oral Immune Priming Treatment Alters Microbiome Composition in the Red Flour BeetleFrontiers in microbiology · 2022Article
- Host Resistance to Bacterial Infection Varies Over Time, but Is Not Affected by a Previous Exposure to the Same Pathogen.Frontiers in physiology · 2022Article
- Influence ofInternational journal of molecular sciences · 2021Article
- Experimental Infection of theMicroorganisms · 2021Article
- The Tripartite Interaction of Host Immunity-Toxins · 2020Review
- Gut Bacteria in the Holometabola: A Review of Obligate and Facultative Symbionts.Journal of insect science (Online) · 2020Review
- Legacy of a Butterfly's Parental Microbiome in Offspring Performance.Applied and environmental microbiology · 2020Article
- Article
- Article
- The Enhanced Immune Protection in Chinese Mitten CrabFrontiers in immunology · 2019Article
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Authors and funding
3 authors.
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Abstract
Animals are inhabited by a diverse community of microorganisms. The relevance of such microbiota is increasingly being recognized across a broad spectrum of species, ranging from sponges to primates, revealing various beneficial roles that microbes can play. The red flour beetle Tribolium castaneum represents a well-established experimental model organism for studying questions in ecology and evolution, however, the relevance of its microbial community is still largely unknown. T. castaneum larvae orally exposed to bacterial components of the entomopathogen Bacillus thuringiensis bv. tenebrionis showed increased survival upon a subsequent challenge with spores of this bacterium. To investigate whether T. castaneum microbiota plays a role in this phenomenon, we established a protocol for raising microbe-free larvae and subsequently tested whether they differ in their ability to mount such a priming response. Here we demonstrate that larvae with significantly lowered microbial loads, show decreased survival upon secondary challenge with B. thuringiensis bv. tenebrionis spores, compared to animals that were allowed to regain their microbiota before priming. Although the exact mechanism of oral immune priming is unclear, we here suggest that microbiota plays a crucial role in oral immune priming in this species.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.