ReviewFrontiers in physiology2015
The Impact of Different Environmental Conditions on Cognitive Function: A Focused Review.
Review in Frontiers in physiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04138446 (Effects of Acute Hypobaric Hypoxia Exposure on Neurocognitive Performance of Pre-hospital Emergency Service Providers), which is not on this map. Cited by 150 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effects of Acute Hypobaric Hypoxia Exposure on Neurocognitive Performance of Pre-hospital Emergency Service Providers
Who cites it
150 citing papers in PubMed, 5 syntheses or guidelines pooled it, 354 citations in OpenAlex.
- A Meta-Analysis of Multidimensional Cognitive Functions Changes in Different Intensities of High-Altitude Hypoxia.Brain and behavior · 2025Pooled it
- Determining Cognitive Performance in Athletes: A Systematic Review Focused on Methodology of Applying Cognitive Tests.Scandinavian journal of psychology · 2025Pooled it
- Effects of hypohydration and fluid balance in athletes' cognitive performance: a systematic review.African health sciences · 2022Pooled it
- Is altitude a determinant of the health benefits of nature exposure? A systematic review and meta-analysis.Frontiers in public health · 2022Pooled it
- Does exercise have a protective effect on cognitive function under hypoxia? A systematic review with meta-analysis.Journal of sport and health science · 2020Pooled it
- Does a pharmacologically driven elevation in cerebral blood flow modulate cognition during combined hypoxic and thermal stress?Journal of applied physiology (Bethesda, Md. : 1985) · 2026Trial
- Inhalation of phlai-containing essential oil enhances cognition: a comparison with olive oil in healthy adults.Frontiers in pharmacology · 2025Trial
- The effect of a combined cooling intervention on cognitive function in the heat during an intermittent running protocol.European journal of sport science · 2024Trial
- Simulated Acute Hypobaric Hypoxia Effects on Cognition in Helicopter Emergency Medical Service Personnel - A Randomized, Controlled, Single-Blind, Crossover Trial.Human factors · 2024Trial
- Acute hypoxia impairs posterior cerebral bioenergetics and memory in man.Experimental physiology · 2023Trial
- Concomitant dual-site tDCS and dark chocolate improve cognitive and endurance performance following cognitive effort under hypoxia: a randomized controlled trial.Scientific reports · 2023Trial
- Effect of acetazolamide on visuomotor performance at high altitude in healthy people 40 years of age or older-RCT.PloS one · 2023Trial
- Trial
- Marine Survival in the Mediterranean: A Pilot Study on the Cognitive and Cardiorespiratory Response to Sudden Cool Water Immersion.International journal of environmental research and public health · 2022Trial
- Impact of acute partial-body cryostimulation on cognitive performance, cerebral oxygenation, and cardiac autonomic activity.Scientific reports · 2021Trial
- Impact of elevated core temperature on cognition in hot environments within a military context.European journal of applied physiology · 2021Trial
- Different Amounts of Water Supplementation Improved Cognitive Performance and Mood among Young Adults after 12 h Water Restriction in Baoding, China: A Randomized Controlled Trial (RCT).International journal of environmental research and public health · 2020Trial
- Heat, menstruation, and mental health in adolescence and young adulthood: Understudied in climate-health research.Dialogues in health · 2026Review
- A Comprehensive Assessment of Physiological and Neural Changes Underlying Cognitive Performance after Heat Stress: A Randomized Clinical Trial.Environment & health (Washington, D.C.) · 2026Article
- Acute lack of sunlight exposure is associated with poorer cognitive test performance: evidence from two national cohorts in the United Kingdom.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2026Article
90 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cognitive function defines performance in objective tasks that require conscious mental effort. Extreme environments, namely heat, hypoxia, and cold can all alter human cognitive function due to a variety of psychological and/or biological processes. The aims of this Focused Review were to discuss; (1) the current state of knowledge on the effects of heat, hypoxic and cold stress on cognitive function, (2) the potential mechanisms underpinning these alterations, and (3) plausible interventions that may maintain cognitive function upon exposure to each of these environmental stressors. The available evidence suggests that the effects of heat, hypoxia, and cold stress on cognitive function are both task and severity dependent. Complex tasks are particularly vulnerable to extreme heat stress, whereas both simple and complex task performance appear to be vulnerable at even at moderate altitudes. Cold stress also appears to negatively impact both simple and complex task performance, however, the research in this area is sparse in comparison to heat and hypoxia. In summary, this focused review provides updated knowledge regarding the effects of extreme environmental stressors on cognitive function and their biological underpinnings. Tyrosine supplementation may help individuals maintain cognitive function in very hot, hypoxic, and/or cold conditions. However, more research is needed to clarify these and other postulated interventions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.