Evidence map›Paper›PMID 26778834›Full record

ArticleJournal of biomedical informatics2016

The genomic CDS sandbox: An assessment among domain experts.

Ayesha Aziz, Kensaku Kawamoto, Karen Eilbeck, Marc S Williams, Robert R Freimuth, Mark A Hoffman, Luke V Rasmussen, Casey L Overby, Brian H Shirts, James M Hoffman and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of biomedical informatics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Big Data Analytics for Genomic Medicine.International journal of molecular sciences · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Ayesha AzizMedical University of South Carolina, Charleston, SC, United States. Electronic address: aziza@musc.edu.
Kensaku KawamotoUniversity of Utah, Salt Lake City, UT, United States. Electronic address: kensaku.kawamoto@utah.edu.
Karen EilbeckUniversity of Utah, Salt Lake City, UT, United States. Electronic address: keilbeck@genetics.utah.edu.
Marc S WilliamsGeisinger Medical Center, Danville, PA, United States. Electronic address: mswilliams1@geisinger.edu.
Robert R FreimuthMayo Clinic, Rochester, MN, United States. Electronic address: Freimuth.Robert@mayo.edu.
Mark A HoffmanUniversity of Missouri-Kansas City, MO, United States. Electronic address: hoffmanma@umkc.edu.
Luke V RasmussenNorthwestern University, Chicago, IL, United States. Electronic address: luke.rasmussen@northwestern.edu.
Casey L OverbyUniversity of Maryland, Baltimore, MD, United States. Electronic address: coverby@medicine.umaryland.edu.
Brian H ShirtsUniversity of Washington, Seattle, United States. Electronic address: shirtsb@uw.edu.
James M HoffmanSt. Jude Children's Research Hospital, Memphis, TN, United States. Electronic address: james.hoffman@stjude.org.
Brandon M WelchMedical University of South Carolina, Charleston, SC, United States. Electronic address: welchbm@musc.edu.

Funding

Northwestern University Clinical and Translational Science Institute (NUCATS)UL1TR001422 · NCATS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI D'AQUILA, RICHARD · 2015 to 2023
$56.8M
Pharmacogenetics of Phase II Drug Metabolizing EnzymesU19GM061388 · NIGMS · MAYO CLINIC ROCHESTER · PI WEINSHILBOUM, RICHARD M. · 2010 to 2014
$15.8M
Genomic Medicine at Northwestern: Discovery and ImplementationU01HG008673 · NHGRI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI CHISHOLM, REX L, SMITH, MAUREEN E · 2015 to 2019
$4.1M
NCATS NIH HHS UL1 TR001422NHGRI NIH HHS U01 HG008673NIGMS NIH HHS U19 GM061388
6 · The paper itself

Abstract

Genomics is a promising tool that is becoming more widely available to improve the care and treatment of individuals. While there is much assertion, genomics will most certainly require the use of clinical decision support (CDS) to be fully realized in the routine clinical setting. The National Human Genome Research Institute (NHGRI) of the National Institutes of Health recently convened an in-person, multi-day meeting on this topic. It was widely recognized that there is a need to promote the innovation and development of resources for genomic CDS such as a CDS sandbox. The purpose of this study was to evaluate a proposed approach for such a genomic CDS sandbox among domain experts and potential users. Survey results indicate a significant interest and desire for a genomic CDS sandbox environment among domain experts. These results will be used to guide the development of a genomic CDS sandbox.

Indexed as

Computational BiologyDecision Support Systems, ClinicalCongresses as TopicGenomicsHumansNational Human Genome Research Institute (U.S.)SoftwareUnited StatesClinical decision support systemsGenomicsHealth information technologyMedical geneticsPersonalized medicine

Identifiers

PMID26778834
PMCPMC4948866

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.