Evidence map›Paper›PMID 26778778›Full record

ArticleBrain, behavior, and immunity2016

Does education lower allostatic load? A co-twin control study.

Nayla R Hamdi, Susan C South, Robert F Krueger

Abstract readTwin Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Brain, behavior, and immunity, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. The Role of Epigenetic Clocks in Explaining Educational Inequalities in Mortality: A Multicohort Study and Meta-analysis.The journals of gerontology. Series A, Biological sciences and medical sciences · 2022
    Pooled it
  3. Article
  4. Resilience to Maltreatment in Early Adulthood Does Not Predict Low Allostatic Load at Midlife.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2023
    Article
  5. Article
  6. Article
  7. Can I Buy My Health? A Genetically Informed Study of Socioeconomic Status and Health.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Nayla R HamdiDepartment of Psychology, University of Minnesota, 75 E River Road, Minneapolis, MN 55455, USA. Electronic address: naylahamdi@gmail.com.
Susan C SouthDepartment of Psychology, Purdue University, 703 Third Street, West Lafayette, IN 47907, USA. Electronic address: ssouth@psych.purdue.edu.
Robert F KruegerDepartment of Psychology, University of Minnesota, 75 E River Road, Minneapolis, MN 55455, USA. Electronic address: krueg038@umn.edu.

Funding

U19 MIDlife in the United States-Diversity Supplement-WellsU19AG051426 · NIA · UNIVERSITY OF WISCONSIN-MADISON · PI CHRISTOPHER L COE · 2016 to 2026
$74.8M
STATISTICS COREP01AG020166 · NIA · UNIVERSITY OF WISCONSIN-MADISON · PI RYFF, CAROL D. · 2002 to 2015
$50.6M
NIA NIH HHS P01 AG020166NIA NIH HHS U19 AG051426
6 · The paper itself

Abstract

Many studies have found that education is associated with better health, but the causal basis of this association is unclear. The current study used a co-twin control design to examine if differences in years of education within twin pairs predict allostatic load. The strength of this design is that it controls for genetic and other familial confounds shared between twins. The sample consisted of 381 twins (with 292 twins from 146 complete pairs; mean age=57; 61% female) who participated in the biomarker project of the Midlife Development in the United States (MIDUS) study. Individual-level analyses showed a significant, negative association between years of education and allostatic load, but this association was explained entirely by familial influences shared between twins. The results of this study suggest that schooling does not itself protect against allostatic load.

Indexed as

Educational StatusAdultAgedAged, 80 and overAllostasisFemaleHumansMaleMiddle AgedUnited StatesAllostatic loadCo-twin controlDiscordant twinEducationHealth

Identifiers

PMID26778778
PMCPMC4917427

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.