Evidence map›Paper›PMID 26778488›Full record

ReviewJournal of the American Medical Directors Association2016

Antimicrobial Stewardship in Long-Term Care Facilities: A Call to Action.

Haley J Morrill, Aisling R Caffrey, Robin L P Jump, David Dosa, Kerry L LaPlante

Abstract readReview
In one paragraph

Review in Journal of the American Medical Directors Association, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Review
  8. Article
  9. Holistically sustainable continence care: A working definition, the case of single-used absorbent hygiene products (AHPs) and the need for ecosystems thinking.Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine · 2024
    Review
  10. Review
  11. Infection control in long term care institutions for the elderly: A reflection document on the situation in Spain.Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia · 2023
    Review
  12. Review
  13. Review
  14. Article
  15. The Association Between Nursing Home Information Technology Maturity and Urinary Tract Infection Among Long-Term Residents.Journal of applied gerontology : the official journal of the Southern Gerontological Society · 2022
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Haley J MorrillCenter of Innovation for Long-term Services and Supports, Veterans Affairs Medical Center, Providence, RI; Infectious Diseases Research Program, Veterans Affairs Medical Center, Providence, RI; Department of Pharmacy Practice, College of Pharmacy, University of Rhode Island, Kingston, RI. Electronic address: haley.morrill@va.gov.
Aisling R CaffreyCenter of Innovation for Long-term Services and Supports, Veterans Affairs Medical Center, Providence, RI; Infectious Diseases Research Program, Veterans Affairs Medical Center, Providence, RI; Department of Pharmacy Practice, College of Pharmacy, University of Rhode Island, Kingston, RI.
Robin L P JumpGeriatric Research Education and Clinical Center (GRECC) and Infectious Diseases Section, Louis Stokes Cleveland VA Medical Center, Cleveland, OH; Division of Infectious Disease and HIV Medicine, Department of Medicine, Case Western Reserve University, Cleveland, OH.
David DosaCenter of Innovation for Long-term Services and Supports, Veterans Affairs Medical Center, Providence, RI; Division of Infectious Diseases, Warren Alpert Medical School of Brown University, Providence, RI.
Kerry L LaPlanteCenter of Innovation for Long-term Services and Supports, Veterans Affairs Medical Center, Providence, RI; Infectious Diseases Research Program, Veterans Affairs Medical Center, Providence, RI; Department of Pharmacy Practice, College of Pharmacy, University of Rhode Island, Kingston, RI; Division of Infectious Diseases, Warren Alpert Medical School of Brown University, Providence, RI.

Funding

Clinical and Translational Science Collaborative of ClevelandUL1TR000439 · NCATS · CASE WESTERN RESERVE UNIVERSITY · PI KONSTAN, MICHAEL W. · 2012 to 2016
$50.0M
Improving Antimicrobial Stewardship in Veterans Affairs (VA) Community Living CentersI01HX001894 · VA · PROVIDENCE VA MEDICAL CENTER · PI DOSA, DAVID M., MD, MPH · 2018 to 2020
–
HSRD VA I01 HX001894NCATS NIH HHS UL1 TR000439NCATS NIH HHS UL1TR000439
6 · The paper itself

Abstract

Antimicrobial resistance is a global public health crisis and a national security threat to the United States, as stated in an executive order signed by the president in September 2014. This crisis is a result of indiscriminant antimicrobial use, which promotes selection for resistant organisms, increases the risk of adverse drug events, and renders patients vulnerable to drug-resistant infections. Antimicrobial stewardship is a key measure to combat antimicrobial resistance and specifically seeks to do this by improving antimicrobial use. Antimicrobial stewardship compliments infection control practices and it is important to note that these 2 disciplines are distinct and cannot be discussed interchangeably. Antimicrobial stewardship promotes the appropriate diagnosis, drug, dose, and duration of treatment. The appropriate diagnosis falls into the hands of the prescriber and clinical staff. Optimal antimicrobial drug selection, dosing strategy, and duration of treatment, however, often require expertise in antimicrobial therapy, such as an infectious disease-trained physician or pharmacist. Therefore, successful antimicrobial stewardship programs must be comprehensive and interdisciplinary. Most antimicrobial stewardship programs focus on hospitals; yet, in long-term care, up to 75% of antimicrobial use is inappropriate or unnecessary. Thus, one of the most pressing areas in need for antimicrobial stewardship is in long-term care facilities. Unfortunately, there is little evidence that describes effective antimicrobial stewardship interventions in this setting. This review discusses the need for and barriers to antimicrobial stewardship in long-term care facilities. Additionally, this review describes prior interventions that have been implemented and tested to improve antimicrobial use in long-term care facilities.

Indexed as

Drug Resistance, MicrobialInappropriate PrescribingNursing HomesAnti-Infective AgentsHumansAnti-Infective Agentsantibiotic useantimicrobial resistanceAntimicrobial stewardship programlong-term carenursing home

Identifiers

PMID26778488
PMCPMC6348872

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.