ArticleDiagnostic microbiology and infectious disease2016
Whole genome multilocus sequence typing as an epidemiologic tool for Yersinia pestis.
Article in Diagnostic microbiology and infectious disease, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Small Insertions and Deletions Drive Genomic Plasticity during Adaptive Evolution of Yersinia pestis.Microbiology spectrum · 2022Review
- Similar yet different: phylogenomic analysis to delineate Salmonella and Citrobacter species boundaries.BMC genomics · 2020Article
- The Cano-eMLST Program: An Approach for the Calculation of Canonical Extended Multi-Locus Sequence Typing, Making Comparison of Genetic Differences Among Bunches of Bacterial Strains.Microorganisms · 2019Article
- Francisella tularensis Transmission by Solid Organ Transplantation, 2017Emerging infectious diseases · 2019Article
- Epidemiological Typing of Serratia marcescens Isolates by Whole-Genome Multilocus Sequence Typing.Journal of clinical microbiology · 2019Article
- Evaluating sub-typing methods for pathogenic Yersinia enterocolitica to support outbreak investigations in New Zealand.Epidemiology and infection · 2019Article
- Next-generation sequencing technologies and their application to the study and control of bacterial infections.Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases · 2018Review
- Human case of bubonic plague resulting from the bite of a wild Gunnison's prairie dog during translocation from a plague-endemic area.Zoonoses and public health · 2018Article
- Large-scale genomic analyses reveal the population structure and evolutionary trends of Streptococcus agalactiae strains in Brazilian fish farms.Scientific reports · 2017Article
- Whole-Genome Sequencing of Bacterial Pathogens: the Future of Nosocomial Outbreak Analysis.Clinical microbiology reviews · 2017Review
- Next-Generation Epidemiology: Using Real-Time Core Genome Multilocus Sequence Typing To Support Infection Control Policy.Journal of clinical microbiology · 2016Article
- Investigation of and Response to 2 Plague Cases, Yosemite National Park, California, USA, 2015.Emerging infectious diseases · 2016Article
- Whole-Genome Multilocus Sequence Typing of Extended-Spectrum-Beta-Lactamase-Producing Enterobacteriaceae.Journal of clinical microbiology · 2016Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
Human plague is a severe and often fatal zoonotic disease caused by Yersinia pestis. For public health investigations of human cases, nonintensive whole genome molecular typing tools, capable of defining epidemiologic relationships, are advantageous. Whole genome multilocus sequence typing (wgMLST) is a recently developed methodology that simplifies genomic analyses by transforming millions of base pairs of sequence into character data for each gene. We sequenced 13 US Y. pestis isolates with known epidemiologic relationships. Sequences were assembled de novo, and multilocus sequence typing alleles were assigned by comparison against 3979 open reading frames from the reference strain CO92. Allele-based cluster analysis accurately grouped the 13 isolates, as well as 9 publicly available Y. pestis isolates, by their epidemiologic relationships. Our findings indicate wgMLST is a simplified, sensitive, and scalable tool for epidemiologic analysis of Y. pestis strains.
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