Evidence map›Paper›PMID 26777053›Full record

ArticleEuropean journal of cancer care2017

The symptom phenotype of oncology outpatients remains relatively stable from prior to through 1 week following chemotherapy.

C Miaskowski, B A Cooper, B Aouizerat, M Melisko, L-M Chen, L Dunn, X Hu, K M Kober, J Mastick, J D Levine and 9 more

Abstract readMulticenter Study
In one paragraph

Article in European journal of cancer care, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Article
  4. Review
  5. Article
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  7. Article
  8. The prevalence and risk of symptom and function clusters in colorectal cancer survivors.Journal of cancer survivorship : research and practice · 2022
    Article
  9. Article
  10. Subgroups of patients undergoing chemotherapy with distinct cognitive fatigue and evening physical fatigue profiles.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021
    Article
  11. Distinct profiles of multiple co-occurring symptoms in patients with gastrointestinal cancers receiving chemotherapy.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021
    Article
  12. Article
  13. Higher levels of stress and different coping strategies are associated with greater morning and evening fatigue severity in oncology patients receiving chemotherapy.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2020
    Article
  14. Co-occurrence of decrements in physical and cognitive function is common in older oncology patients receiving chemotherapy.European journal of oncology nursing : the official journal of European Oncology Nursing Society · 2020
    Article
  15. Article
  16. Article
  17. Co-occuring symptoms in older oncology patients with distinct attentional function profiles.European journal of oncology nursing : the official journal of European Oncology Nursing Society · 2019
    Article
  18. Article
  19. Article
  20. Distinct attentional function profiles in older adults receiving cancer chemotherapy.European journal of oncology nursing : the official journal of European Oncology Nursing Society · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

C MiaskowskiSchool of Nursing, University of California, San Francisco, CA, USA.
B A CooperSchool of Nursing, University of California, San Francisco, CA, USA.
B AouizeratCollege of Dentistry, New York University, New York, NY, USA.
M MeliskoSchool of Medicine, University of California, San Francisco, CA, USA.
L-M ChenSchool of Medicine, University of California, San Francisco, CA, USA.
L DunnSchool of Medicine, University of California, San Francisco, CA, USA.
X HuSchool of Nursing, University of California, San Francisco, CA, USA.
K M KoberSchool of Nursing, University of California, San Francisco, CA, USA.
J MastickSchool of Nursing, University of California, San Francisco, CA, USA.
J D LevineSchool of Medicine, University of California, San Francisco, CA, USA.
M HammerNew York University College of Nursing, New York, NY, USA.
F WrightSchool of Nursing, Yale University, New Haven, CT, USA.
J HarrisFlorence Nightingale Faculty of Nursing and Midwifery, King's College London, London, UK.ORCID http://orcid.org/0000-0001-8933-117X
J ArmesFlorence Nightingale Faculty of Nursing and Midwifery, King's College London, London, UK.
E FurlongSchool of Nursing, Midwifery, and Health Systems, University College Dublin, Dublin, Ireland.
P FoxSchool of Nursing, Midwifery, and Health Systems, University College Dublin, Dublin, Ireland.
E ReamSchool of Health Sciences, University of Surrey, Guilford, UK.
R MaguireSchool of Health Sciences, University of Surrey, Guilford, UK.
N KearneySchool of Health Sciences, University of Surrey, Guilford, UK.

Funding

Symptoms Clusters in Oncology Patients Receiving ChemotherapyR01CA134900 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI AOUIZERAT, BRADLEY E, MIASKOWSKI, CHRISTINE A. · 2009 to 2014
$5.9M
NCI NIH HHS R01 CA134900
6 · The paper itself

Abstract

Some oncology outpatients experience a higher number of and more severe symptoms during chemotherapy (CTX). However, little is known about whether this high risk phenotype persists over time. Latent transition analysis (LTA) was used to examine the probability that patients remained in the same symptom class when assessed prior to the administration of and following their next dose of CTX. For the patients whose class membership remained consistent, differences in demographic and clinical characteristics, and quality of life (QOL) were evaluated. The Memorial Symptom Assessment Scale (MSAS) was used to evaluate symptom burden. LTA was used to identify subgroups of patients with distinct symptom experiences based on the occurrence of the MSAS symptoms. Of the 906 patients evaluated, 83.9% were classified in the same symptom occurrence class at both assessments. Of these 760 patients, 25.0% were classified as Low-Low, 44.1% as Moderate-Moderate and 30.9% as High-High. Compared to the Low-Low class, the other two classes were younger, more likely to be women and to report child care responsibilities, and had a lower functional status and a higher comorbidity scores. The two higher classes reported lower QOL scores. The use of LTA could assist clinicians to identify higher risk patients and initiate more aggressive interventions.

Indexed as

AdolescentAdultAgedAmbulatory CareAntineoplastic AgentsFemaleHealth StatusHumansMaleMental HealthMiddle AgedNeoplasmsOutpatientsPhenotypeQuality of LifeTime FactorsAntineoplastic Agentscancerchemotherapylatent transition analysispredictive risk modellingquality of lifesymptoms

Identifiers

PMID26777053
PMCPMC7233145

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.