Evidence map›Paper›PMID 26776215›Full record

ArticlePacific Symposium on Biocomputing. Pacific Symposium on Biocomputing2016

FINDING POTENTIALLY UNSAFE NUTRITIONAL SUPPLEMENTS FROM USER REVIEWS WITH TOPIC MODELING.

Ryan Sullivan, Abeed Sarker, Karen O'Connor, Amanda Goodin, Mark Karlsrud, Graciela Gonzalez

Abstract read
In one paragraph

Article in Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Serious Skin Injuries Following Exposure to Unapproved Mole and Skin Tag Removers.The Journal of clinical and aesthetic dermatology · 2023
    Article
  3. The Evaluation of Videos about Branched-Chain Amino Acids Supplements on YouTubeInternational journal of environmental research and public health · 2022
    Article
  4. Review
  5. Article
  6. Article
  7. iDISK: the integrated DIetary Supplements Knowledge base.Journal of the American Medical Informatics Association : JAMIA · 2020
    Article
  8. Article
  9. Article
  10. Biomedical Text Categorization Based on Ensemble Pruning and Optimized Topic Modelling.Computational and mathematical methods in medicine · 2018
    Article
  11. Review
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ryan SullivanDepartment of Biomedical Informatics, Arizona State University, Scottsdale, AZ 85259, USA, rpsulli@asu.edu.
Abeed Sarker
Karen O'Connor
Amanda Goodin
Mark Karlsrud
Graciela Gonzalez

Funding

Social Media Mining for PharmacovigilanceR01LM011176 · NLM · UNIVERSITY OF PENNSYLVANIA · PI GONZALEZ HERNANDEZ, GRACIELA, SHEN, LI · 2012 to 2021
$4.5M
NLM NIH HHS R01 LM011176PHS HHS FDU001418
6 · The paper itself

Abstract

Although dietary supplements are widely used and generally are considered safe, some supplements have been identified as causative agents for adverse reactions, some of which may even be fatal. The Food and Drug Administration (FDA) is responsible for monitoring supplements and ensuring that supplements are safe. However, current surveillance protocols are not always effective. Leveraging user-generated textual data, in the form of Amazon.com reviews for nutritional supplements, we use natural language processing techniques to develop a system for the monitoring of dietary supplements. We use topic modeling techniques, specifically a variation of Latent Dirichlet Allocation (LDA), and background knowledge in the form of an adverse reaction dictionary to score products based on their potential danger to the public. Our approach generates topics that semantically capture adverse reactions from a document set consisting of reviews posted by users of specific products, and based on these topics, we propose a scoring mechanism to categorize products as "high potential danger", "average potential danger" and "low potential danger." We evaluate our system by comparing the system categorization with human annotators, and we find that the our system agrees with the annotators 69.4% of the time. With these results, we demonstrate that our methods show promise and that our system represents a proof of concept as a viable low-cost, active approach for dietary supplement monitoring.

Indexed as

Adverse Drug Reaction Reporting SystemsAlgorithmsComputational BiologyData MiningDietary SupplementsHazard Analysis and Critical Control PointsHumansInternetMachine LearningModels, StatisticalNatural Language ProcessingPharmacovigilancePublic Health SurveillanceSocial MediaUnited StatesUnited States Food and Drug Administration

Identifiers

PMID26776215
PMCPMC6391886

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.