ReviewSeminars in fetal & neonatal medicine2016
Cervical etiology of spontaneous preterm birth.
Review in Seminars in fetal & neonatal medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
67 citing papers in PubMed.
- Longitudinal ultrasonic dimensions and parametric solid models of the gravid uterus and cervix.PloS one · 2021Trial
- Biomechanical function of the murine cervix with elastic fiber deficiency.Journal of the mechanical behavior of biomedical materials · 2026Article
- A finite element model of pregnancy derived from maternal sonography: effect of uterine and cervical structural properties on cervical mechanical loading.bioRxiv : the preprint server for biology · 2026Article
- A new perspective on predicting latency period in preterm premature rupture of membranes: the role of cervical area measurement.Irish journal of medical science · 2026Article
- Risk of preterm birth and peripartal complications after first trimester termination of pregnancy: a retrospective cohort study of 35,897 singleton births.Archives of gynecology and obstetrics · 2026Article
- Reframing Cervical Insufficiency as a Dynamic Process in the Preterm Birth Continuum: From Fixed Disease to a Modifiable Condition.Diagnostics (Basel, Switzerland) · 2026Article
- Arachidonic Acid-Induced Contraction of Smooth Muscle Is Mediated by MLC Phosphorylation in Preterm Birth.Journal of pregnancy · 2026Article
- Spectrum of Cervical Insufficiency: Management Strategies from Asymptomatic Shortening to Emergent Membrane Prolapse.Journal of clinical medicine · 2025Review
- Discovering latent subtypes of preterm birth and genetic risk using tensor decomposition on electronic health records.medRxiv : the preprint server for health sciences · 2025Article
- The Lioness™ device: a prospective non-randomized safety and feasibility study of a novel device for preterm birth delay and prevention.BMC pregnancy and childbirth · 2025Article
- Shotgun metagenomics of the vaginal microbiome in cervical shortening and preterm birth risk.Scientific reports · 2025Article
- A Comparative Study of the Effect of Commonly Used Pesticides on Cervical Contractions in Pregnant Cows, In Vitro.Toxics · 2025Article
- Women's Pregnancy Experiences With a Transvaginal Cervical Cerclage: A Qualitative Study.BJOG : an international journal of obstetrics and gynaecology · 2025Article
- Cervical sliding sign and cervical funneling in the third trimester as predictors of spontaneous preterm birth in singleton pregnancy.Quantitative imaging in medicine and surgery · 2025Article
- Cellular dynamics of cervical remodelling: insights from preterm and term labour.Archives of gynecology and obstetrics · 2025Observational
- Review
- Equilibrium Mechanical Properties of the Nonhuman Primate Cervix.Journal of biomechanical engineering · 2024Article
- Analysis of the impact of maternal sepsis on pregnancy outcomes: a population-based retrospective study.BMC pregnancy and childbirth · 2024Article
- Article
- Urogenital cultures and preterm birth in women with cervical cerclage: a single center retrospective cohort study.BMC pregnancy and childbirth · 2024Article
7 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
The cervix functions as a barrier between the uterus and vagina and keeps the uterus closed until term so that the fetus can develop. For delivery the cervix must soften and dilate, and finally reconstitute to close the uterus. This complex process involves precisely timed activation of molecular and microstructural events. Spontaneous preterm birth (sPTB) can result from aberrant timing of these events in the cervix. Unfortunately, the pathophysiology of sPTB due to cervical causes remains unclear and thus our treatment options remain limited - even if all appropriate candidates were identified and correctly treated with currently available interventions, the rate of sPTB would only be reduced by 5%. Very recent molecular and microstructural investigation is challenging prevailing concepts about cervical remodeling in pregnancy. We believe that progress toward novel, targeted solutions for the diverse pathways to sPTB entails a paradigm shift in which the overlapping and complex interactions between the cervix, uterus, membranes, fetus, placenta, and surrounding (structural and molecular) environment are suitably honored.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.