Evidence map›Paper›PMID 26776084›Full record

ArticleJournal of clinical epidemiology2016

Improved incidence estimates from linked vs. stand-alone electronic health records.

Elizabeth R C Millett, Jennifer K Quint, Bianca L De Stavola, Liam Smeeth, Sara L Thomas

Open access · hybridAbstract readComparative Study
In one paragraph

Article in Journal of clinical epidemiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
5.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 46 citations in OpenAlex.

  1. Article
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  4. Article
  5. Analysis of incidence of motor neuron disease in England 1998-2019: use of three linked datasets.Amyotrophic lateral sclerosis & frontotemporal degeneration · 2022
    Article
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  11. Article
  12. Article
  13. Observational
  14. Article
  15. Big Data's Role in Precision Public Health.Frontiers in public health · 2018
    Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Elizabeth R C MillettDepartment of Infectious Disease Epidemiology, Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK. Electronic address: elizabeth.millett@ndm.ox.ac.uk.
Jennifer K QuintDepartment of Non-communicable Disease Epidemiology, Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK.
Bianca L De StavolaDepartment of Medical Statistics, Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, Keppel Street, London, WC1E 7HT, UK.
Liam SmeethDepartment of Non-communicable Disease Epidemiology, Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK.
Sara L ThomasDepartment of Infectious Disease Epidemiology, Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK.
University of London · GBLondon School of Hygiene & Tropical Medicine · GB

Funding

Department of Health CDF-2010-03-32Medical Research Council G0902135Medical Research Council MR/K006584/1Wellcome Trust 098504/Z/12/Z
6 · The paper itself

Abstract

objectiveElectronic health records are widely used for public health research, and linked data sources are increasingly available. The added value of using linked records over stand-alone data has not been quantified for common conditions such as community-acquired pneumonia (CAP). STUDY DESIGN AND

settingOur cohort comprised English patients aged ≥65 years from the Clinical Practice Research Datalink, eligible for record linkage to Hospital Episode Statistics. Stand-alone general practice (GP) records were used to calculate CAP incidence over time using population-averaged Poisson regression. Incidence was then recalculated for the same patients using their linked GP-hospital admission data. Results of the two analyses were compared.

resultsOver 900,000 patients were included in each analysis. Population-averaged CAP incidence was 39% higher using the linked data than stand-alone data. This difference grew over time from 7% in 1997 to 83% by 2010. An increasingly larger number of pneumonia events were recorded in the hospital admission data compared to the GP data over time.

conclusionUse of primary or secondary care data in isolation may not give accurate incidence estimates for important infections in older populations. Further work is needed to establish the extent of this finding in other diseases, age groups, and populations.

Indexed as

Epidemiologic Research DesignAgedCommunity-Acquired InfectionsElectronic Health RecordsEnglandFemaleGeneral PracticeGeriatric AssessmentHumansIncidenceMaleAgedCohortData linkageElectronic health recordsEngland/epidemiologyPneumonia

Identifiers

PMID26776084
PMCPMC4922622
OpenAlexW2226119967

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.