ArticleNeuropsychologia2016
The relationships between the amount of spared tissue, percent signal change, and accuracy in semantic processing in aphasia.
Article in Neuropsychologia, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
32 citing papers in PubMed, 54 citations in OpenAlex.
- Language comprehension in chronic aphasia relies on the language network, not the Multiple Demand network.medRxiv : the preprint server for health sciences · 2026Article
- Dynamic functional reorganization in post-stroke aphasia: a state-of-the-art fMRI review from disease evolution to intervention.Frontiers in neuroscience · 2026Review
- PICTURE-IT: a pilot randomized cross-over trial encouraging right-hemisphere engagement for the treatment of aphasia via telemedicine.Aphasiology · 2025Article
- Dynamic reorganization of task-related network interactions in post-stroke aphasia recovery.Brain : a journal of neurology · 2025Article
- Independent contributions of language activations in left and right temporal cortex to aphasia outcomes after stroke.medRxiv : the preprint server for health sciences · 2025Article
- EEG reveals brain network alterations in chronic aphasia during natural speech listening.Scientific reports · 2025Article
- Individualized connectomic tACS immediately improves oscillatory network with language facilitation in post-stroke aphasia: a feasibility study of a dysfunctome-based targeting approach.Frontiers in computational neuroscience · 2025Article
- Remapping and Reconnecting the Language Network after Stroke.Brain sciences · 2024Review
- Disentangling neuroplasticity mechanisms in post-stroke language recovery.Brain and language · 2024Review
- Pars Opercularis Underlies Efferent Predictions and Successful Auditory Feedback Processing in Speech: Evidence From Left-Hemisphere Stroke.Neurobiology of language (Cambridge, Mass.) · 2024Article
- Treatment-induced neural reorganization in aphasia is language-domain specific: Evidence from a large-scale fMRI study.Cortex; a journal devoted to the study of the nervous system and behavior · 2023Article
- Dynamic alterations of spontaneous neural activity in post-stroke aphasia: a resting-state functional magnetic resonance imaging study.Frontiers in neuroscience · 2023Article
- French Phonological Component Analysis and aphasia recovery: A bilingual perspective on behavioral and structural data.Frontiers in human neuroscience · 2022Article
- Abnormally weak functional connections get stronger in chronic stroke patients who benefit from naming therapy.Brain and language · 2021Article
- Representation of semantic typicality in brain activation in healthy adults and individuals with aphasia: A multi-voxel pattern analysis.Neuropsychologia · 2021Article
- Neuroplasticity in post-stroke aphasia: A systematic review and meta-analysis of functional imaging studies of reorganization of language processing.Neurobiology of language (Cambridge, Mass.) · 2021Article
- Investigating Language and Domain-General Processing in Neurotypicals and Individuals With Aphasia - A Functional Near-Infrared Spectroscopy Pilot Study.Frontiers in human neuroscience · 2021Article
- Pre-treatment graph measures of a functional semantic network are associated with naming therapy outcomes in chronic aphasia.Brain and language · 2020Article
- The Domain-General Multiple Demand (MD) Network Does Not Support Core Aspects of Language Comprehension: A Large-Scale fMRI Investigation.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2020Article
- fMRI reveals language-specific predictive coding during naturalistic sentence comprehension.Neuropsychologia · 2020Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
Abstract
Recovery from aphasia, loss of language following a cerebrovascular incident (stroke), is a complex process involving both left and right hemispheric regions. In our study, we analyzed the relationships between semantic processing behavioral data, lesion size and location, and percent signal change from functional magnetic resonance imaging (fMRI) data. This study included 14 persons with aphasia in the chronic stage of recovery (six or more months post stroke), along with normal controls, who performed semantic processing tasks of determining whether a written semantic feature matched a picture or whether two written words were related. Using region of interest (ROI) analysis, we found that left inferior frontal gyrus pars opercularis and pars triangularis, despite significant damage, were the only regions to correlate with behavioral accuracy. Additionally, bilateral frontal regions including superior frontal gyrus, middle frontal gyrus, and anterior cingulate appear to serve as an assistive network in the case of damage to traditional language regions that include inferior frontal gyrus, middle temporal gyrus, supramarginal gyrus, and angular gyrus. Right hemisphere posterior regions including right middle temporal gyrus, right supramarginal gyrus, and right angular gyrus are engaged in the case of extensive damage to left hemisphere language regions. Additionally, right inferior frontal gyrus pars orbitalis is presumed to serve a monitoring function. These results reinforce the importance of the left hemisphere in language processing in aphasia, and provide a framework for the relative importance of left and right language regions in the brain.
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Registered trials
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