ArticleHeart rhythm2016
Cardiac Purkinje fibers and arrhythmias; The GK Moe Award Lecture 2015.
Article in Heart rhythm, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
25 citing papers in PubMed, 45 citations in OpenAlex.
- Idiopathic Ventricular Fibrillation Triggered by Purkinje-Related Extrasystoles: State-of-the-Art and Novel Therapeutic Approaches.Journal of cardiovascular electrophysiology · 2026Review
- Mechanism of Arrhythmogenesis Driven by Early After Depolarizations in Cardiac Tissue.PLoS computational biology · 2025Article
- The role of DPP6 dysregulation in neuropathology: from synaptic regulation to disease mechanisms.Frontiers in cellular neuroscience · 2025Review
- Transcriptional regulation of the postnatal cardiac conduction system heterogeneity.Nature communications · 2024Article
- AAV9-mediated SMN gene therapy rescues cardiac desmin but not lamin A/C and elastin dysregulation in Smn2B/- spinal muscular atrophy mice.Human molecular genetics · 2023Article
- Moderator Band and Ventricular Tachycardia: Structural or Functional Substrate?Journal of cardiovascular development and disease · 2023Review
- Conduction delays across the specialized conduction system of the heart: Revisiting atrioventricular node (AVN) and Purkinje-ventricular junction (PVJ) delays.Frontiers in cardiovascular medicine · 2023Article
- Endocardial role in arrhythmias induced by acute ventricular stretch and the involvement of Purkinje fibres, in isolated rat hearts.Current research in physiology · 2023Article
- Critical Requirements for the Initiation of a Cardiac Arrhythmia in Rat Ventricle: How Many Myocytes?Cells · 2022Article
- 3D magnetization transfer (MT) for the visualization of cardiac free-running Purkinje fibers: an ex vivo proof of concept.Magma (New York, N.Y.) · 2021Article
- Sinoatrial node pacemaker cells share dominant biological properties with glutamatergic neurons.Protein & cell · 2021Article
- Reduced NaAmerican journal of physiology. Heart and circulatory physiology · 2020Article
- Arrhythmias from the Right Ventricular Moderator Band: Diagnosis and Management.Arrhythmia & electrophysiology review · 2020Review
- TRANSCRIPTIONAL REGULATION OF THE CARDIAC CONDUCTION SYSTEM.Transactions of the American Clinical and Climatological Association · 2020Article
- Article
- A novel graphene oxide polymer gel platform for cardiac tissue engineering application.3 Biotech · 2019Article
- Prevention of ventricular fibrillation through de-networking of the Purkinje system: Proof-of-Concept Paper on the Substrate Modification of the Purkinje Network.Pacing and clinical electrophysiology : PACE · 2019Article
- A Light Wand to Untangle the Myocardial Cell Network.Methods and protocols · 2019Review
- Small-conductance calcium-activated potassium current modulates the ventricular escape rhythm in normal rabbit hearts.Heart rhythm · 2019Article
- Premature MicroRNA-1 Expression Causes Hypoplasia of the Cardiac Ventricular Conduction System.Frontiers in physiology · 2019Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Purkinje fibers/cells continue to be a focus of arrhythmologists. Here we review several new ideas that have emerged in the literature and fold them into important new points. These points include the following: some proteins in Purkinje cells are specific to Purkinjes; pacemaker function in Purkinje may be similar to that of the sinus node cell; sink-source concerns about tracts/sheets of Purkinje fibers; role of Ito in arrhythmias; and genetic lesions in Purkinjes and their high impact on cardiac rhythm. Although new ideas about the remodeled Purkinje cell are not the focus of this review, one can easily imagine how Purkinjes and their function may be altered in diseased hearts.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.