ArticleNeuroImage2016
Trade-off between angular and spatial resolutions in in vivo fiber tractography.
Article in NeuroImage, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The Role of White Matter in the Neural Control of Swallowing: A Systematic Review.Frontiers in human neuroscience · 2021Pooled it
- A Novel Fixel-Based Approach for Resolving Neonatal White Matter Microstructure from Clinical Diffusion MRI.medRxiv : the preprint server for health sciences · 2026Article
- A novel fixel-based approach for resolving neonatal white matter microstructure from clinical diffusion MRI.Frontiers in neuroscience · 2026Article
- White Matter Bundle Reconstruction From Single-Shell Diffusion Magnetic Resonance Imaging: Test-Retest Reliability and Predictive Capability Across Orientation Distribution Function Reconstruction Methods.Human brain mapping · 2025Article
- Super-resolution mapping of anisotropic tissue structure with diffusion MRI and deep learning.Scientific reports · 2025Article
- An image quality transfer approach for localising deep brain stimulation targets.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Surface-based tracking for short association fibre tractography.NeuroImage · 2022Article
- Fast Fiber Orientation Estimation in Diffusion MRI from kq-Space Sampling and Anatomical Priors.Journal of imaging · 2021Article
- Diffusion tractography for awake craniotomy: accuracy and factors affecting specificity.Journal of neuro-oncology · 2021Article
- In vivo human whole-brain Connectom diffusion MRI dataset at 760 µm isotropic resolution.Scientific data · 2021Article
- Whole mouse brain connectomics.The Journal of comparative neurology · 2019Article
- Building connectomes using diffusion MRI: why, how and but.NMR in biomedicine · 2019Review
- Diffusion-based tractography atlas of the human acoustic radiation.Scientific reports · 2019Article
- Deficits in mesolimbic reward pathway underlie social interaction impairments in children with autism.Brain : a journal of neurology · 2018Article
- The effect of pulsatile motion and cardiac-gating on reconstruction and diffusion tensor properties of the corticospinal tract.Scientific reports · 2018Article
- Connectome-derived diffusion characteristics of the fornix in Alzheimer's disease.NeuroImage. Clinical · 2018Article
- Altered white matter connectivity in patients with schizophrenia: An investigation using public neuroimaging data from SchizConnect.PloS one · 2018Article
- Meyer's loop tractography for image-guided surgery depends on imaging protocol and hardware.NeuroImage. Clinical · 2018Article
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Authors and funding
8 authors.
Funding
Abstract
Tractography is becoming an increasingly popular method to reconstruct white matter connections in vivo. The diffusion MRI data that tractography is based on requires a high angular resolution to resolve crossing fibers whereas high spatial resolution is required to distinguish kissing from crossing fibers. However, scan time increases with increasing spatial and angular resolutions, which can become infeasible in clinical settings. Here we investigated the trade-off between spatial and angular resolutions to determine which of these factors is most worth investing scan time in. We created a unique diffusion MRI dataset with 1.0 mm isotropic resolution and a high angular resolution (100 directions) using an advanced 3D diffusion-weighted multi-slab EPI acquisition. This dataset was reconstructed to create subsets of lower angular (75, 50, and 25 directions) and lower spatial (1.5, 2.0, and 2.5 mm) resolution. Using all subsets, we investigated the effects of angular and spatial resolutions in three fiber bundles-the corticospinal tract, arcuate fasciculus and corpus callosum-by analyzing the volumetric bundle overlap and anatomical correspondence between tracts. Our results indicate that the subsets of 25 and 50 directions provided inferior tract reconstructions compared with the datasets with 75 and 100 directions. Datasets with spatial resolutions of 1.0, 1.5, and 2.0 mm were comparable, while the lowest resolution (2.5 mm) datasets had discernible inferior quality. In conclusion, we found that angular resolution appeared to be more influential than spatial resolution in improving tractography results. Spatial resolutions higher than 2.0 mm only appear to benefit multi-fiber tractography methods if this is not at the cost of decreased angular resolution.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.