Evidence map›Paper›PMID 26774073›Full record

Observational studyPediatric pulmonology2016

Sex differences in the association between neck circumference and asthma.

Lisa Maltz, Ethan L Matz, Heather Gordish-Dressman, Dinesh K Pillai, Stephen J Teach, Carlos A Camargo, Monica J Hubal, Simran Behniwal, Guy D Prosper, Nicole Certner and 6 more

Abstract readObservational Study
In one paragraph

Observational study in Pediatric pulmonology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Asthma interactions between obesity and other risk factors.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2022
    Review
  2. Asthma and Obstructive Sleep Apnea Overlap: What Has the Evidence Taught Us?American journal of respiratory and critical care medicine · 2020
    Review
  3. Article
  4. Review
  5. Article
  6. Obesity and asthma.The Journal of allergy and clinical immunology · 2018
    Review
  7. Article
  8. Article
  9. Review
  10. The effect of obesity, weight gain, and weight loss on asthma inception and control.Current opinion in allergy and clinical immunology · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Lisa MaltzCenter for Genetic Medicine Research, Children's National Health System, Washington, DC.
Ethan L MatzGeorge Washington University School of Medicine and Health Sciences, Washington, DC.
Heather Gordish-DressmanCenter for Genetic Medicine Research, Children's National Health System, Washington, DC.
Dinesh K PillaiCenter for Genetic Medicine Research, Children's National Health System, Washington, DC.
Stephen J TeachDepartment of Pediatrics, George Washington University School of Medicine and Health Sciences, Washington, DC.
Carlos A CamargoDepartment of Emergency Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.
Monica J HubalCenter for Genetic Medicine Research, Children's National Health System, Washington, DC.
Simran BehniwalCenter for Genetic Medicine Research, Children's National Health System, Washington, DC.
Guy D ProsperCenter for Genetic Medicine Research, Children's National Health System, Washington, DC.
Nicole CertnerCenter for Genetic Medicine Research, Children's National Health System, Washington, DC.
Raman MarwahCenter for Genetic Medicine Research, Children's National Health System, Washington, DC.
Douglas M MansellCenter for Genetic Medicine Research, Children's National Health System, Washington, DC.
Fisayo NwachukwuCenter for Genetic Medicine Research, Children's National Health System, Washington, DC.
Risa LazaroffCenter for Genetic Medicine Research, Children's National Health System, Washington, DC.
Yodit TsegayeGeorge Washington University School of Medicine and Health Sciences, Washington, DC.
Robert J FreishtatCenter for Genetic Medicine Research, Children's National Health System, Washington, DC.

Funding

Clinical and Translational Science Institute at Children's NationalUL1TR000075 · NCATS · CHILDREN'S RESEARCH INSTITUTE · PI GUAY-WOODFORD, LISA MARIE · 2012 to 2015
$13.7M
Vitamin D, Steroids, and Asthma in African American YouthR01MD007075 · NIMHD · CHILDREN'S RESEARCH INSTITUTE · PI FREISHTAT, ROBERT J · 2012 to 2016
$2.2M
NCATS NIH HHS UL1 TR000075NIMHD NIH HHS R01 MD007075
6 · The paper itself

Abstract

introductionThe association between obesity and asthma control/quality of life commonly relies on body mass index (BMI) as the anthropomorphic measure. Due to limitations of BMI and the existence of alternative measures, such as neck circumference (NC), we examined the association between NC and asthma control/quality of life, with particular attention to male-female differences. MATERIALS AND

methodsThe AsthMaP-2 Project is an observational study of youth with physician-diagnosed asthma. NC was stratified according to age- and sex-specific cutoffs and associated with asthma control (via Asthma Control Test [ACT]) and quality of life (via Integrated Therapeutics Group [ITG]-Asthma Short Form).

resultsThe mean ± SD age was 11.9 ± 3.6 years, and 53% were male (N = 116). The mean BMI percentile was at the 71 ± 28 percentile. Thirty-one participants (27%) met criteria for high NC. Males with high NC had significantly worse asthma control (P = 0.02) and lower quality of life than those with low NC. No similar association was found for females and the proportion of variability in ACT and ITG was best explained by BMI percentile. Conversely, for males, the proportion of variability in these scores explained by NC was larger than BMI percentile alone (Cohen's f(2)  = 0.04-0.09, a small to medium effect size). DISCUSSION: Among male youth with asthma, combined use of NC and BMI percentile explained asthma control and quality of life better than BMI alone. Future studies of asthma should include measurement of NC and other anthropogenic measures of regional adiposity to clarify sex differences in asthma. Pediatr Pulmonol. 2016; 51:893-900. © 2016 Wiley Periodicals, Inc.

Indexed as

Body Mass IndexQuality of LifeAdiposityAdolescentAsthmaChildFemaleHumansMaleNeckObesitySex FactorsYoung Adultadipositybody mass indexpediatric obesitypediatrics

Identifiers

PMID26774073
PMCPMC5266754

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.