Evidence map›Paper›PMID 26773825›Full record

ArticleHealth economics2016

Parameterising User Uptake in Economic Evaluations: The role of discrete choice experiments.

Fern Terris-Prestholt, Matthew Quaife, Peter Vickerman

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In one paragraph

Article in Health economics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
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  3. How well do discrete choice experiments predict health choices? A systematic review and meta-analysis of external validity.The European journal of health economics : HEPAC : health economics in prevention and care · 2018
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  9. Patient Preferences for Longer or More Frequent In-Center Hemodialysis Regimens: A Multicenter Discrete Choice Study.American journal of kidney diseases : the official journal of the National Kidney Foundation · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Fern Terris-PrestholtSocial and Mathematical Epidemiology (SaME), Department of Global Health and Development, London School of Hygiene & Tropical Medicine, London, UK.
Matthew QuaifeSocial and Mathematical Epidemiology (SaME), Department of Global Health and Development, London School of Hygiene & Tropical Medicine, London, UK.
Peter VickermanSocial and Mathematical Epidemiology (SaME), Department of Global Health and Development, London School of Hygiene & Tropical Medicine, London, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Model-based economic evaluations of new interventions have shown that user behaviour (uptake) is a critical driver of overall impact achieved. However, early economic evaluations, prior to introduction, often rely on assumed levels of uptake based on expert opinion or uptake of similar interventions. In addition to the likely uncertainty surrounding these uptake assumptions, they also do not allow for uptake to be a function of product, intervention, or user characteristics. This letter proposes using uptake projections from discrete choice experiments (DCE) to better parameterize uptake and substitution in cost-effectiveness models. A simple impact model is developed and illustrated using an example from the HIV prevention field in South Africa. Comparison between the conventional approach and the DCE-based approach shows that, in our example, DCE-based impact predictions varied by up to 50% from conventional estimates and provided far more nuanced projections. In the absence of observed uptake data and to model the effect of variations in intervention characteristics, DCE-based uptake predictions are likely to greatly improve models parameterizing uptake solely based on expert opinion. This is particularly important for global and national level decision making around introducing new and probably more expensive interventions, particularly where resources are most constrained.

Indexed as

Choice BehaviorHealth Care CostsModels, EconomicConsumer BehaviorCost-Benefit AnalysisDecision MakingEconomics, MedicalHealth Services ResearchHumansSouth Africadiscrete choice experimentseconomic evaluationlow-income and middle-income countrymathematical modellinguptakeuser preferences

Identifiers

PMID26773825
PMCPMC5066644

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.