ArticleMuscle & nerve2016
Gender-specific neuromuscular adaptations to unloading in isolated rat soleus muscles.
Article in Muscle & nerve, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
5 citing papers in PubMed.
- Hindlimb Suspension and Subsequent Weight-Loading on Femoral Morphology, Knee Joint Alignment, and Patellar Tracking in Growing Rats.Journal of musculoskeletal & neuronal interactions · 2025Article
- Mature and Juvenile Neuromuscular Plasticity in Response to Unloading.Developmental neurobiology · 2025Article
- Adaptation to full weight-bearing following disuse in rats: The impact of biological sex on musculoskeletal recovery.Physiological reports · 2024Article
- Hindlimb suspension in Wistar rats: Sex-based differences in muscle response.Physiological reports · 2021Article
- Gender-specific analysis for the association between trunk muscle mass and spinal pathologies.Scientific reports · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
introductionThe potential of gender to affect unloading-induced neuromuscular adaptations was investigated.
methodsTwenty male and 20 female rats were assigned to control (CTL), or unloaded (UL) conditions. After 2 weeks of unloading, soleus muscles were removed, and neuromuscular function was assessed during a train of alternating indirect (neural) and direct (muscle) stimuli.
resultsIn rested muscle, strength showed significant (P ≤ 0.05) main effects for gender (male > female) and treatment (CTL > UL). By the end of the testing protocol, when muscles showed fatigue, gender-related and treatment-related differences in strength had disappeared. Neuromuscular transmission efficiency and strength suffered a greater decline during the testing protocol in males than females. Unloaded male muscles displayed greater contractile velocity than female muscles both when rested and fatigued.
conclusionsGender affected unloading-induced neuromuscular adaptations. The greater strength of rested male muscles was due to greater muscle mass and neuromuscular transmission efficiency. Muscle Nerve 54: 300-307, 2016.
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