Evidence map›Paper›PMID 26773014›Full record

ReviewAdvances in nutrition (Bethesda, Md.)2016

Red Raspberries and Their Bioactive Polyphenols: Cardiometabolic and Neuronal Health Links.

Britt M Burton-Freeman, Amandeep K Sandhu, Indika Edirisinghe

Abstract readReview
In one paragraph

Review in Advances in nutrition (Bethesda, Md.), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 72 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
72citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

72 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Polyphenols for the Prevention or Management of Preeclampsia: A Systematic Review and Meta-Analysis.BJOG : an international journal of obstetrics and gynaecology · 2025
    Pooled it
  2. Trial
  3. Trial
  4. Trial
  5. Article
  6. Raspberry protective role in inflammatory diseases: An overview.Iranian journal of basic medical sciences · 2026
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Review
  13. Review
  14. Polyphenolic Compounds in the Stems of Raspberry (Molecules (Basel, Switzerland) · 2024
    Article
  15. Article
  16. Review
  17. Article
  18. Review
  19. Article
  20. Article

12 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Britt M Burton-FreemanCenter for Nutrition Research, Institute for Food Safety and Health, Illinois Institute of Technology, Bedford Park, IL; and Department of Nutrition, University of California, Davis, CA bburton@iit.edu.
Amandeep K SandhuCenter for Nutrition Research, Institute for Food Safety and Health, Illinois Institute of Technology, Bedford Park, IL; and.
Indika EdirisingheCenter for Nutrition Research, Institute for Food Safety and Health, Illinois Institute of Technology, Bedford Park, IL; and.

Funding

National Center for Food Safety and TechnologyU19FD005322 · FDA · ILLINOIS INSTITUTE OF TECHNOLOGY · PI Brian Todd Schaneberg · 2014 to 2026
$52.7M
FDA HHS U19 FD005322
6 · The paper itself

Abstract

Diet is an essential factor that affects the risk of modern-day metabolic diseases, including cardiovascular disease, diabetes mellitus, obesity, and Alzheimer disease. The potential ability of certain foods and their bioactive compounds to reverse or prevent the progression of the pathogenic processes that underlie these diseases has attracted research attention. Red raspberries (Rubus idaeus L.) are unique berries with a rich history and nutrient and bioactive composition. They possess several essential micronutrients, dietary fibers, and polyphenolic components, especially ellagitannins and anthocyanins, the latter of which give them their distinctive red coloring. In vitro and in vivo studies have revealed various mechanisms through which anthocyanins and ellagitannins (via ellagic acid or their urolithin metabolites) and red raspberry extracts (or the entire fruit) could reduce the risk of or reverse metabolically associated pathophysiologies. To our knowledge, few studies in humans are available for evaluation. We review and summarize the available literature that assesses the health-promoting potential of red raspberries and select components in modulating metabolic disease risk, especially cardiovascular disease, diabetes mellitus, obesity, and Alzheimer disease-all of which share critical metabolic, oxidative, and inflammatory links. The body of research is growing and supports a potential role for red raspberries in reducing the risk of metabolically based chronic diseases.

Indexed as

PhytotherapyAlzheimer DiseaseCardiovascular DiseasesFruitHumansMetabolic DiseasesPlant ExtractsPolyphenolsRubusPlant ExtractsPolyphenolsanthocyaninscardiovascular diseasediabetesellagic acidinflammationoxidative stresspolyphenolsred raspberries

Identifiers

PMID26773014
PMCPMC4717884

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.