ArticlePlant physiology2016
Evolutionary Dynamics of the Leucine-Rich Repeat Receptor-Like Kinase (LRR-RLK) Subfamily in Angiosperms.
Article in Plant physiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 68 papers.
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Who cites it
68 citing papers in PubMed, 162 citations in OpenAlex.
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- GbWAKL20 Phosphorylates GbNFYB8 to Modulate Verticillium Wilt Resistance in Cotton.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Identification of HSF gene family and functional analysis of two HSFA1 genes with tandem repeat features in Fritillaria cirrhosa D.Don.BMC genomics · 2026Article
- Deciphering the role of receptor-like kinases in the adaptation ofFrontiers in plant science · 2026Article
- Genetic Diversity, Predictive Protein Structures, and Interaction Networks of Cysteine-Rich Receptor-Like Kinases inComputational and structural biotechnology journal · 2026Article
- The apoplastic protein OsCPIP8 confers dual protection by inhibiting pathogenic protease and activating rice immunity.Nature communications · 2025Article
- A molecular perspective on the role of FERONIA in root growth, nutrient uptake, stress sensing and microbiome assembly.Journal of advanced research · 2025Review
- Article
- A conserved Phytophthora apoplastic trypsin-like serine protease targets the receptor-like kinase BAK1 to dampen plant immunity.Nature plants · 2025Article
- Genome identification of the LRR-RLK gene family in maize (Zea mays) and expression analysis in response to Fusarium verticillioides infection.BMC plant biology · 2025Article
- A haplotype-resolved reference genome of Quercus alba sheds light on the evolutionary history of oaks.The New phytologist · 2025Article
- Preventing inappropriate signals pre- and post-ligand perception by a toggle switch mechanism of ERECTA.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- The Past, Present, and Future of Plant Activators Targeting the Salicylic Acid Signaling Pathway.Genes · 2024Review
- Preventing Inappropriate Signals Pre- and Post-Ligand Perception by a Toggle-Switch Mechanism of ERECTA.bioRxiv : the preprint server for biology · 2024Article
- Leveraging coevolutionary insights and AI-based structural modeling to unravel receptor-peptide ligand-binding mechanisms.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Genome-wide identification of JAZ gene family members in autotetraploid cultivated alfalfa (Medicago sativa subsp. sativa) and expression analysis under salt stress.BMC genomics · 2024Article
- Evolutionary trajectory of pattern recognition receptors in plants.Nature communications · 2024Article
- Article
- Differential expansion and retention patterns of LRR-RLK genes across plant evolution.Plant direct · 2023Article
- Asymmetric Evolution of Protein Domains in the Leucine-Rich Repeat Receptor-Like Kinase Family of Plant Signaling Proteins.Molecular biology and evolution · 2023Article
8 more citing papers are in PubMed but not listed here.
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Gene duplications are an important factor in plant evolution, and lineage-specific expanded (LSE) genes are of particular interest. Receptor-like kinases expanded massively in land plants, and leucine-rich repeat receptor-like kinases (LRR-RLK) constitute the largest receptor-like kinases family. Based on the phylogeny of 7,554 LRR-RLK genes from 31 fully sequenced flowering plant genomes, the complex evolutionary dynamics of this family was characterized in depth. We studied the involvement of selection during the expansion of this family among angiosperms. LRR-RLK subgroups harbor extremely contrasting rates of duplication, retention, or loss, and LSE copies are predominantly found in subgroups involved in environmental interactions. Expansion rates also differ significantly depending on the time when rounds of expansion or loss occurred on the angiosperm phylogenetic tree. Finally, using a dN/dS-based test in a phylogenetic framework, we searched for selection footprints on LSE and single-copy LRR-RLK genes. Selective constraint appeared to be globally relaxed at LSE genes, and codons under positive selection were detected in 50% of them. Moreover, the leucine-rich repeat domains, and specifically four amino acids in them, were found to be the main targets of positive selection. Here, we provide an extensive overview of the expansion and evolution of this very large gene family.
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