ArticleThe Plant cell2016
Genome Reduction Uncovers a Large Dispensable Genome and Adaptive Role for Copy Number Variation in Asexually Propagated Solanum tuberosum.
Article in The Plant cell, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 101 papers.
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Who cites it
101 citing papers in PubMed.
- Quantitative trait loci for Globodera pallida resistance derived from wild potato species Solanum gourlayi.Journal of applied genetics · 2026Article
- Genomic constraint and hypervariability correlate with fitness effects in elite tetraploid potato breeding material.PLoS genetics · 2026Article
- nTChap: an accurate method for polyploid haplotype reconstruction.BMC genomics · 2026Article
- Human selection maintains karyotype integrity of highly unstable genomic cultivated autotetraploid potato (Science advances · 2025Article
- Review
- Chromosome level assembly and annotation of Cuscuta campestris Yunck. ("field dodder"), a model parasitic plant.G3 (Bethesda, Md.) · 2025Article
- New Insights into the Role of Secondary Metabolic Pathways in Resistance of Potato toInternational journal of molecular sciences · 2025Article
- FHY3/FAR1 transposable elements generate adaptive genetic variation in the Bassia scoparia genome.Pest management science · 2025Article
- A Systematic Review of the Advances and New Insights into Copy Number Variations in Plant Genomes.Plants (Basel, Switzerland) · 2025Review
- Transcriptomics-proteomics analysis reveals StCOMT1 regulates drought, alkali and combined stresses in potato.Plant cell reports · 2025Article
- Identification of Gene Targets for the Sprouting Inhibitor CIPC.Plant direct · 2025Article
- SpudDB: a database for accessing potato genomic data.Genetics · 2025Article
- A comprehensive map of DNA-segment copy number variation in 491 genomes of common wheat uncovers genes associated with multiple agronomic traits.Plant communications · 2025Article
- Elucidating the molecular basis of salt tolerance in potatoes through miRNA expression and phenotypic analysis.Scientific reports · 2025Article
- Genome-wide identification and expression pattern analysis of the chloride channel gene family in potato (Frontiers in plant science · 2025Article
- Long-read sequencing reveals novel structural variation markers for key agronomic and quality traits of food-grade soybean.Frontiers in plant science · 2025Article
- Genome-Wide Identification ofInternational journal of molecular sciences · 2024Article
- A stepwise guide for pangenome development in crop plants: an alfalfa (Medicago sativa) case study.BMC genomics · 2024Review
- Chromosome-scale Salvia hispanica L. (Chia) genome assembly reveals rampant Salvia interspecies introgression.The plant genome · 2024Article
- The phased Solanum okadae genome and Petota pangenome analysis of 23 other potato wild relatives and hybrids.Scientific data · 2024Article
41 more citing papers are in PubMed but not listed here.
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16 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Clonally reproducing plants have the potential to bear a significantly greater mutational load than sexually reproducing species. To investigate this possibility, we examined the breadth of genome-wide structural variation in a panel of monoploid/doubled monoploid clones generated from native populations of diploid potato (Solanum tuberosum), a highly heterozygous asexually propagated plant. As rare instances of purely homozygous clones, they provided an ideal set for determining the degree of structural variation tolerated by this species and deriving its minimal gene complement. Extensive copy number variation (CNV) was uncovered, impacting 219.8 Mb (30.2%) of the potato genome with nearly 30% of genes subject to at least partial duplication or deletion, revealing the highly heterogeneous nature of the potato genome. Dispensable genes (>7000) were associated with limited transcription and/or a recent evolutionary history, with lower deletion frequency observed in genes conserved across angiosperms. Association of CNV with plant adaptation was highlighted by enrichment in gene clusters encoding functions for environmental stress response, with gene duplication playing a part in species-specific expansions of stress-related gene families. This study revealed unique impacts of CNV in a species with asexual reproductive habits and how CNV may drive adaption through evolution of key stress pathways.
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